5,8-Dimethyl-9<i>H</i>-carbazole Derivatives Blocking hTopo I Activity and Actin Dynamics

5,8-Dimethyl-9<i>H</i>-carbazole Derivatives Blocking hTopo I Activity and Actin Dynamics

Over the years, carbazoles have been largely studied for their numerous biological properties, including antibacterial, antimalarial, antioxidant, antidiabetic, neuroprotective, anticancer, and many more. Some of them have gained great interest for their anticancer activity in breast cancer due to t...

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Bibliographic Details
Main Authors: Jessica Ceramella, Domenico Iacopetta, Anna Caruso, Annaluisa Mariconda, Anthi Petrou, Athina Geronikaki, Camillo Rosano, Carmela Saturnino, Alessia Catalano, Pasquale Longo, Maria Stefania Sinicropi
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceuticals
Subjects:
human topoisomerases I/II
anticancer
docking simulation
actin dynamics
Online Access:https://www.mdpi.com/1424-8247/16/3/353

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