An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification

Glaucoma, an eye disease, occurs due to Retinal damages and it is an ordinary cause of blindness. Most of the available examining procedures are too long and require manual instructions to use them. In this work, we proposed a multi-level deep convolutional neural network (ML-DCNN) architecture on r...

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Main Authors: Muhammad Aamir, Muhammad Irfan, Tariq Ali, Ghulam Ali, Ahmad Shaf, Alqahtani Saeed S, Ali Al-Beshri, Tariq Alasbali, Mater H. Mahnashi
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/10/8/602
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author Muhammad Aamir
Muhammad Irfan
Tariq Ali
Ghulam Ali
Ahmad Shaf
Alqahtani Saeed S
Ali Al-Beshri
Tariq Alasbali
Mater H. Mahnashi
author_facet Muhammad Aamir
Muhammad Irfan
Tariq Ali
Ghulam Ali
Ahmad Shaf
Alqahtani Saeed S
Ali Al-Beshri
Tariq Alasbali
Mater H. Mahnashi
author_sort Muhammad Aamir
collection DOAJ
description Glaucoma, an eye disease, occurs due to Retinal damages and it is an ordinary cause of blindness. Most of the available examining procedures are too long and require manual instructions to use them. In this work, we proposed a multi-level deep convolutional neural network (ML-DCNN) architecture on retinal fundus images to diagnose glaucoma. We collected a retinal fundus images database from the local hospital. The fundus images are pre-processed by an adaptive histogram equalizer to reduce the noise of images. The ML-DCNN architecture is used for features extraction and classification into two phases, one for glaucoma detection known as detection-net and the second one is classification-net used for classification of affected retinal glaucoma images into three different categories: Advanced, Moderate and Early. The proposed model is tested on 1338 retinal glaucoma images and performance is measured in the form of different statistical terms known as sensitivity (SE), specificity (SP), accuracy (ACC), and precision (PRE). On average, SE of 97.04%, SP of 98.99%, ACC of 99.39%, and PRC of 98.2% are achieved. The obtained outcomes are comparable to the state-of-the-art systems and achieved competitive results to solve the glaucoma eye disease problems for complex glaucoma eye disease cases.
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spelling doaj.art-c24ed26ba8684ae9b88e2ff408e166b52023-11-20T10:28:48ZengMDPI AGDiagnostics2075-44182020-08-0110860210.3390/diagnostics10080602An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and ClassificationMuhammad Aamir0Muhammad Irfan1Tariq Ali2Ghulam Ali3Ahmad Shaf4Alqahtani Saeed S5Ali Al-Beshri6Tariq Alasbali7Mater H. Mahnashi8Department of Computer Science, COMSATS University Islamabad Sahiwal Campus, Sahiwal 57000, PakistanCollege of Engineering, Electrical Engineering Department, Najran University, Najran 61441, Saudi ArabiaCollege of Engineering, Electrical Engineering Department, Najran University, Najran 61441, Saudi ArabiaDepartment of Computer Science, University of Okara, Okara 56300, PakistanDepartment of Computer Science, COMSATS University Islamabad Sahiwal Campus, Sahiwal 57000, PakistanDepartment of Surgery, Faculty of Medicine, Najran University, Najran 61441, Saudi ArabiaKing Khalid Eye Specialist Hospital, Riyadh 12329, Saudi ArabiaDepartment of Ophthalmology, College of Medicine, Al Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 4233-13317, Saudi ArabiaDepartment of Pharmaceutical Chemistry, College of Pharmacy, Najran University, Najran 61441, Saudi ArabiaGlaucoma, an eye disease, occurs due to Retinal damages and it is an ordinary cause of blindness. Most of the available examining procedures are too long and require manual instructions to use them. In this work, we proposed a multi-level deep convolutional neural network (ML-DCNN) architecture on retinal fundus images to diagnose glaucoma. We collected a retinal fundus images database from the local hospital. The fundus images are pre-processed by an adaptive histogram equalizer to reduce the noise of images. The ML-DCNN architecture is used for features extraction and classification into two phases, one for glaucoma detection known as detection-net and the second one is classification-net used for classification of affected retinal glaucoma images into three different categories: Advanced, Moderate and Early. The proposed model is tested on 1338 retinal glaucoma images and performance is measured in the form of different statistical terms known as sensitivity (SE), specificity (SP), accuracy (ACC), and precision (PRE). On average, SE of 97.04%, SP of 98.99%, ACC of 99.39%, and PRC of 98.2% are achieved. The obtained outcomes are comparable to the state-of-the-art systems and achieved competitive results to solve the glaucoma eye disease problems for complex glaucoma eye disease cases.https://www.mdpi.com/2075-4418/10/8/602ML-DCNNglaucoma deep-learningcomputer visionconvolutional neural networkglaucoma eye disease
spellingShingle Muhammad Aamir
Muhammad Irfan
Tariq Ali
Ghulam Ali
Ahmad Shaf
Alqahtani Saeed S
Ali Al-Beshri
Tariq Alasbali
Mater H. Mahnashi
An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification
Diagnostics
ML-DCNN
glaucoma deep-learning
computer vision
convolutional neural network
glaucoma eye disease
title An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification
title_full An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification
title_fullStr An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification
title_full_unstemmed An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification
title_short An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification
title_sort adoptive threshold based multi level deep convolutional neural network for glaucoma eye disease detection and classification
topic ML-DCNN
glaucoma deep-learning
computer vision
convolutional neural network
glaucoma eye disease
url https://www.mdpi.com/2075-4418/10/8/602
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