Central Serous Chorioretinopathy Risk Factors in An Iranian Cohort: A Case-control Study
Abstract Purpose: This study aimed to investigate the possible risk factors of central serous chorioretinopathy (CSCR) in an Iranian cohort. Methods: We recruited 39 consecutive CSCR cases and 80 age-matched controls with no ocular pathology from the same medical center from March 2019 to March 2021...
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| Format: | Article |
| Language: | English |
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Knowledge E
2023-11-01
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| Series: | Journal of Ophthalmic & Vision Research |
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| Online Access: | https://doi.org/10.18502/jovr.v18i4.14553 |
| _version_ | 1797361101579485184 |
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| author | Saeed Karimi Nastaran Payandeh Sahar Mahmoudi Nejad Azar Hosein Nouri Seyed-Hossein Abtahi |
| author_facet | Saeed Karimi Nastaran Payandeh Sahar Mahmoudi Nejad Azar Hosein Nouri Seyed-Hossein Abtahi |
| author_sort | Saeed Karimi |
| collection | DOAJ |
| description | Abstract Purpose: This study aimed to investigate the possible risk factors of central serous chorioretinopathy (CSCR) in an Iranian cohort. Methods: We recruited 39 consecutive CSCR cases and 80 age-matched controls with no ocular pathology from the same medical center from March 2019 to March 2021. Enrolled patients underwent complete ophthalmological examination and extensive history taking in a referral setting. Logistic regression analysis was performed to detect any possible association of potential risk factors with CSCR. Results: The mean age of CSCR patients was 40.69 ± 7.71 years. The male-to-female ratio in cases and controls was 1:1.79 and 1.22:1, respectively. Logistic regression analysis revealed that alcohol consumption (odds ratio, OR: 62.0, P < 0.001), smoking (OR: 4.0, 95% CI: 1.47-10.85, P < 0.006), corticosteroid use (OR: 6.95, 95% CI: 2.64-18.28, P < 0.001), and high psychological stress (OR: 13.34, 95% CI: 4.68-38.02, P < 0.01) were significant risk factors for developing CSCR. Ischemic heart disease ( P =0.550), hypertension ( P =0.750), and hyperopia ( P =0.467) were not associated with the risk of CSCR. The most common form of steroid use was oral in both groups. No pregnant female was present in the study sample, precluding the assessment of its potential association with CSCR. Conclusion: CSCR often affects individuals of productive working ages; thus, identifying its preventable risk factors is highly encouraged. Our results suggested that alcohol consumption, smoking, and high levels of psychological stress are independent, preventable risk factors for CSCR. |
| first_indexed | 2024-03-08T15:49:09Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 2008-2010 2008-322X |
| language | English |
| last_indexed | 2024-03-08T15:49:09Z |
| publishDate | 2023-11-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Journal of Ophthalmic & Vision Research |
| spelling | doaj.art-c251063423fb48c9b92cd61d02a53f312024-01-09T07:54:41ZengKnowledge EJournal of Ophthalmic & Vision Research2008-20102008-322X2023-11-0118441041610.18502/jovr.v18i4.14553jovr.v18i4.14553Central Serous Chorioretinopathy Risk Factors in An Iranian Cohort: A Case-control StudySaeed Karimi0Nastaran Payandeh1Sahar Mahmoudi Nejad Azar2Hosein Nouri3Seyed-Hossein Abtahi4 Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, IranAbstract Purpose: This study aimed to investigate the possible risk factors of central serous chorioretinopathy (CSCR) in an Iranian cohort. Methods: We recruited 39 consecutive CSCR cases and 80 age-matched controls with no ocular pathology from the same medical center from March 2019 to March 2021. Enrolled patients underwent complete ophthalmological examination and extensive history taking in a referral setting. Logistic regression analysis was performed to detect any possible association of potential risk factors with CSCR. Results: The mean age of CSCR patients was 40.69 ± 7.71 years. The male-to-female ratio in cases and controls was 1:1.79 and 1.22:1, respectively. Logistic regression analysis revealed that alcohol consumption (odds ratio, OR: 62.0, P < 0.001), smoking (OR: 4.0, 95% CI: 1.47-10.85, P < 0.006), corticosteroid use (OR: 6.95, 95% CI: 2.64-18.28, P < 0.001), and high psychological stress (OR: 13.34, 95% CI: 4.68-38.02, P < 0.01) were significant risk factors for developing CSCR. Ischemic heart disease ( P =0.550), hypertension ( P =0.750), and hyperopia ( P =0.467) were not associated with the risk of CSCR. The most common form of steroid use was oral in both groups. No pregnant female was present in the study sample, precluding the assessment of its potential association with CSCR. Conclusion: CSCR often affects individuals of productive working ages; thus, identifying its preventable risk factors is highly encouraged. Our results suggested that alcohol consumption, smoking, and high levels of psychological stress are independent, preventable risk factors for CSCR.https://doi.org/10.18502/jovr.v18i4.14553central serous chorioretinopathyrisk factorssmokingalcohol drinkingpsychological stress |
| spellingShingle | Saeed Karimi Nastaran Payandeh Sahar Mahmoudi Nejad Azar Hosein Nouri Seyed-Hossein Abtahi Central Serous Chorioretinopathy Risk Factors in An Iranian Cohort: A Case-control Study Journal of Ophthalmic & Vision Research central serous chorioretinopathy risk factors smoking alcohol drinking psychological stress |
| title | Central Serous Chorioretinopathy Risk Factors in An Iranian Cohort: A Case-control Study |
| title_full | Central Serous Chorioretinopathy Risk Factors in An Iranian Cohort: A Case-control Study |
| title_fullStr | Central Serous Chorioretinopathy Risk Factors in An Iranian Cohort: A Case-control Study |
| title_full_unstemmed | Central Serous Chorioretinopathy Risk Factors in An Iranian Cohort: A Case-control Study |
| title_short | Central Serous Chorioretinopathy Risk Factors in An Iranian Cohort: A Case-control Study |
| title_sort | central serous chorioretinopathy risk factors in an iranian cohort a case control study |
| topic | central serous chorioretinopathy risk factors smoking alcohol drinking psychological stress |
| url | https://doi.org/10.18502/jovr.v18i4.14553 |
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