Implications of Senescent Cell Burden and NRF2 Pathway in Uremic Calcification: A Translational Study

Implications of Senescent Cell Burden and NRF2 Pathway in Uremic Calcification: A Translational Study

Increased senescent cell burden and dysregulation of the nuclear factor erythroid 2–related factor 2 (NRF2) pathway have been associated with numerous age-related pathologies; however, their role in promoting vascular calcification (VC) in chronic kidney disease (CKD) has yet to be determined. We in...

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Bibliographic Details
Main Authors: Jonas Laget, Sam Hobson, Karen Muyor, Flore Duranton, Irene Cortijo, Piotr Bartochowski, Bernard Jover, Anne-Dominique Lajoix, Magnus Söderberg, Thomas Ebert, Peter Stenvinkel, Àngel Argilés, Karolina Kublickiene, Nathalie Gayrard
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cells
Subjects:
vascular calcification
kidney failure
NRF2
senescence
subtotal nephrectomy
Online Access:https://www.mdpi.com/2073-4409/12/4/643

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