Holmes Tremor Partially Responsive to Topiramate: A Case Report

Background: Holmes tremor is a rare symptomatic movement disorder, characterized by a combination of resting, postural, and intention tremor. It is usually caused by lesions in the brainstem, thalamus, and cerebellum. Despite pharmacological advances, its treatment remains a challenge; many medicati...

Full description

Bibliographic Details
Main Authors: Natalia González Rojas, Martin Cesarini, José L. Etcheverry, Gustavo Da Prat, Tomás Viera Aramburu, Emilia Mabel Gatto
Format: Article
Language:English
Published: Ubiquity Press 2018-06-01
Series:Tremor and Other Hyperkinetic Movements
Subjects:
Online Access:https://tremorjournal.org/index.php/tremor/article/view/565
Description
Summary:Background: Holmes tremor is a rare symptomatic movement disorder, characterized by a combination of resting, postural, and intention tremor. It is usually caused by lesions in the brainstem, thalamus, and cerebellum. Despite pharmacological advances, its treatment remains a challenge; many medications have been used with various degrees of effectiveness. Stereotactic thalamotomy and deep brain stimulation in the ventralis intermedius nucleus have been effective surgical procedures in cases refractory to medical treatment. Case Report: Here we report a young woman with topiramate-responsive Holmes tremor secondary to a brainstem cavernoma. Discussion: Herein we report a Holmes tremor responsive to Topiramate.
ISSN:2160-8288
2160-8288