Review of PP2A Tumor Biology and Antitumor Effects of PP2A Inhibitor LB100 in the Nervous System
Protein phosphatase 2A (PP2A) is a ubiquitous serine/threonine phosphatase implicated in a wide variety of regulatory cellular functions. PP2A is abundant in the mammalian nervous system, and dysregulation of its cellular functions is associated with myriad neurodegenerative disorders. Additionally,...
Main Authors: | Jean-Paul Bryant, Adam Levy, John Heiss, Yeshavanth Kumar Banasavadi-Siddegowda |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-06-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/13/12/3087 |
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