Review of PP2A Tumor Biology and Antitumor Effects of PP2A Inhibitor LB100 in the Nervous System

Review of PP2A Tumor Biology and Antitumor Effects of PP2A Inhibitor LB100 in the Nervous System

Protein phosphatase 2A (PP2A) is a ubiquitous serine/threonine phosphatase implicated in a wide variety of regulatory cellular functions. PP2A is abundant in the mammalian nervous system, and dysregulation of its cellular functions is associated with myriad neurodegenerative disorders. Additionally,...

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Bibliographic Details
Main Authors:	Jean-Paul Bryant, Adam Levy, John Heiss, Yeshavanth Kumar Banasavadi-Siddegowda
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Series:	Cancers
Subjects:	PP2A LB100 nervous system tumor biology brain tumor preclinical
Online Access:	https://www.mdpi.com/2072-6694/13/12/3087

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