Auditory-induced response in the primary sensory cortex of rodents.
The details of auditory response at the subthreshold level in the rodent primary somatosensory cortex, the barrel cortex, have not been studied extensively, although several phenomenological reports have been published. Multisensory features may act as neuronal representations of links between input...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2018-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0209266 |
| _version_ | 1819147156217397248 |
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| author | Atsuko T Maruyama Shoji Komai |
| author_facet | Atsuko T Maruyama Shoji Komai |
| author_sort | Atsuko T Maruyama |
| collection | DOAJ |
| description | The details of auditory response at the subthreshold level in the rodent primary somatosensory cortex, the barrel cortex, have not been studied extensively, although several phenomenological reports have been published. Multisensory features may act as neuronal representations of links between inputs from one sensory modality to other sensory modalities. Here, we examined the basic multisensory postsynaptic responses in the rodent barrel cortex using in vivo whole-cell recordings of neurons. We observed robust responses to acoustic stimuli in most barrel cortex neurons. Acoustically evoked responses were mediated by hearing and reached approximately 60% of the postsynaptic response amplitude elicited by strong somatosensory stimuli. Compared to tactile stimuli, auditory stimuli evoked postsynaptic potentials with a longer latency and longer duration. Specifically, auditory stimuli in barrel cortex neurons appeared to trigger "up states", episodes associated with membrane depolarization and increased synaptic activity. Taken together, our data suggest that barrel cortex neurons have multisensory properties, with distinct synaptic mechanisms underlying tactile and non-tactile responses. |
| first_indexed | 2024-12-22T13:25:20Z |
| format | Article |
| id | doaj.art-c25303723e6d4baead586d7e1787b036 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-22T13:25:20Z |
| publishDate | 2018-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-c25303723e6d4baead586d7e1787b0362022-12-21T18:24:19ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-011312e020926610.1371/journal.pone.0209266Auditory-induced response in the primary sensory cortex of rodents.Atsuko T MaruyamaShoji KomaiThe details of auditory response at the subthreshold level in the rodent primary somatosensory cortex, the barrel cortex, have not been studied extensively, although several phenomenological reports have been published. Multisensory features may act as neuronal representations of links between inputs from one sensory modality to other sensory modalities. Here, we examined the basic multisensory postsynaptic responses in the rodent barrel cortex using in vivo whole-cell recordings of neurons. We observed robust responses to acoustic stimuli in most barrel cortex neurons. Acoustically evoked responses were mediated by hearing and reached approximately 60% of the postsynaptic response amplitude elicited by strong somatosensory stimuli. Compared to tactile stimuli, auditory stimuli evoked postsynaptic potentials with a longer latency and longer duration. Specifically, auditory stimuli in barrel cortex neurons appeared to trigger "up states", episodes associated with membrane depolarization and increased synaptic activity. Taken together, our data suggest that barrel cortex neurons have multisensory properties, with distinct synaptic mechanisms underlying tactile and non-tactile responses.https://doi.org/10.1371/journal.pone.0209266 |
| spellingShingle | Atsuko T Maruyama Shoji Komai Auditory-induced response in the primary sensory cortex of rodents. PLoS ONE |
| title | Auditory-induced response in the primary sensory cortex of rodents. |
| title_full | Auditory-induced response in the primary sensory cortex of rodents. |
| title_fullStr | Auditory-induced response in the primary sensory cortex of rodents. |
| title_full_unstemmed | Auditory-induced response in the primary sensory cortex of rodents. |
| title_short | Auditory-induced response in the primary sensory cortex of rodents. |
| title_sort | auditory induced response in the primary sensory cortex of rodents |
| url | https://doi.org/10.1371/journal.pone.0209266 |
| work_keys_str_mv | AT atsukotmaruyama auditoryinducedresponseintheprimarysensorycortexofrodents AT shojikomai auditoryinducedresponseintheprimarysensorycortexofrodents |