Associations between smoking and alcohol use and arterial elasticity in patients with newly diagnosed essential hypertension: A cross-sectional study
Objective: To assess the relationship between smoking and alcohol use (separately and combined) on arterial stiffness in patients with essential hypertension. Materials and Methods: We assessed never-treated newly diagnosed patients with essential hypertension (n = 446) aged 18–80 years (52% males)...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2017-10-01
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| Series: | Artery Research |
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| Online Access: | https://www.atlantis-press.com/article/125924965/view |
| _version_ | 1828748234669948928 |
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| author | Noor-Ahmed Jatoi Waleed-Ibrahim Al-Baker Afnan Al-Muhanna Fahad Al-Muhanna Stella-Maria Kyvelou Faisal Sharif |
| author_facet | Noor-Ahmed Jatoi Waleed-Ibrahim Al-Baker Afnan Al-Muhanna Fahad Al-Muhanna Stella-Maria Kyvelou Faisal Sharif |
| author_sort | Noor-Ahmed Jatoi |
| collection | DOAJ |
| description | Objective: To assess the relationship between smoking and alcohol use (separately and combined) on arterial stiffness in patients with essential hypertension.
Materials and Methods: We assessed never-treated newly diagnosed patients with essential hypertension (n = 446) aged 18–80 years (52% males). Measurements included aortic stiffness, assessed as pulse wave velocity (PWV) (Complior), wave reflection (augmentation index [AIx]), and transit time [T R] SphygmoCor).
Results: The 446 patients were categorized as: non-smokers (n = 204), ex-smokers (n = 121), current smokers (n = 121), non-drinkers (n = 59), moderate drinkers (n = 281), heavy drinkers (n = 106). Both AIx and PWV were significantly higher in current smokers than in ex-smokers and non-smokers [(p < 0.02), (p < 0.01), respectively]. AIx and PWV were higher in non-drinkers followed by heavy drinkers and moderate drinkers [(p < 0.003), (p < 0.008), respectively]. Among current and ex-smokers there was no significant difference in PWV or AIx by alcohol consumption (p = NS), while in non-smokers AIx was significantly (p < 0.001) higher in the non-drinkers followed by heavy drinkers and those with moderate alcohol consumption and PWV was significantly (p < 0.001) higher in heavy drinkers followed by non-drinkers and those with moderate alcohol consumption.
Conclusion: Moderate alcohol consumption exerts a favorable effect on arterial stiffness in essential hypertensive patients. However, the combined effect of smoking cancels this favorable effect. |
| first_indexed | 2024-04-14T04:58:13Z |
| format | Article |
| id | doaj.art-c2531f6f50b24840b72b3e2fb60d8f9f |
| institution | Directory Open Access Journal |
| issn | 1876-4401 |
| language | English |
| last_indexed | 2024-04-14T04:58:13Z |
| publishDate | 2017-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Artery Research |
| spelling | doaj.art-c2531f6f50b24840b72b3e2fb60d8f9f2022-12-22T02:11:06ZengBMCArtery Research1876-44012017-10-012010.1016/j.artres.2017.10.196Associations between smoking and alcohol use and arterial elasticity in patients with newly diagnosed essential hypertension: A cross-sectional studyNoor-Ahmed JatoiWaleed-Ibrahim Al-BakerAfnan Al-MuhannaFahad Al-MuhannaStella-Maria KyvelouFaisal SharifObjective: To assess the relationship between smoking and alcohol use (separately and combined) on arterial stiffness in patients with essential hypertension. Materials and Methods: We assessed never-treated newly diagnosed patients with essential hypertension (n = 446) aged 18–80 years (52% males). Measurements included aortic stiffness, assessed as pulse wave velocity (PWV) (Complior), wave reflection (augmentation index [AIx]), and transit time [T R] SphygmoCor). Results: The 446 patients were categorized as: non-smokers (n = 204), ex-smokers (n = 121), current smokers (n = 121), non-drinkers (n = 59), moderate drinkers (n = 281), heavy drinkers (n = 106). Both AIx and PWV were significantly higher in current smokers than in ex-smokers and non-smokers [(p < 0.02), (p < 0.01), respectively]. AIx and PWV were higher in non-drinkers followed by heavy drinkers and moderate drinkers [(p < 0.003), (p < 0.008), respectively]. Among current and ex-smokers there was no significant difference in PWV or AIx by alcohol consumption (p = NS), while in non-smokers AIx was significantly (p < 0.001) higher in the non-drinkers followed by heavy drinkers and those with moderate alcohol consumption and PWV was significantly (p < 0.001) higher in heavy drinkers followed by non-drinkers and those with moderate alcohol consumption. Conclusion: Moderate alcohol consumption exerts a favorable effect on arterial stiffness in essential hypertensive patients. However, the combined effect of smoking cancels this favorable effect.https://www.atlantis-press.com/article/125924965/viewSmokingAlcohol consumptionEssential hypertensionArterial stiffness |
| spellingShingle | Noor-Ahmed Jatoi Waleed-Ibrahim Al-Baker Afnan Al-Muhanna Fahad Al-Muhanna Stella-Maria Kyvelou Faisal Sharif Associations between smoking and alcohol use and arterial elasticity in patients with newly diagnosed essential hypertension: A cross-sectional study Artery Research Smoking Alcohol consumption Essential hypertension Arterial stiffness |
| title | Associations between smoking and alcohol use and arterial elasticity in patients with newly diagnosed essential hypertension: A cross-sectional study |
| title_full | Associations between smoking and alcohol use and arterial elasticity in patients with newly diagnosed essential hypertension: A cross-sectional study |
| title_fullStr | Associations between smoking and alcohol use and arterial elasticity in patients with newly diagnosed essential hypertension: A cross-sectional study |
| title_full_unstemmed | Associations between smoking and alcohol use and arterial elasticity in patients with newly diagnosed essential hypertension: A cross-sectional study |
| title_short | Associations between smoking and alcohol use and arterial elasticity in patients with newly diagnosed essential hypertension: A cross-sectional study |
| title_sort | associations between smoking and alcohol use and arterial elasticity in patients with newly diagnosed essential hypertension a cross sectional study |
| topic | Smoking Alcohol consumption Essential hypertension Arterial stiffness |
| url | https://www.atlantis-press.com/article/125924965/view |
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