Stereotactic breast biopsies: Radiological-pathological concordance in a South African referral unit
Background: Stereotactic breast biopsies have become the gold standard for tissue diagnosis in non-palpable, sonographically occult breast abnormalities seen on mammogram. Only limited data exist in South Africa on the correlation between imaging findings and stereotactic biopsy histology. Objectiv...
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| Format: | Article |
| Language: | English |
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AOSIS
2022-08-01
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| Series: | South African Journal of Radiology |
| Subjects: | |
| Online Access: | https://sajr.org.za/index.php/sajr/article/view/2463 |
| _version_ | 1811211122106171392 |
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| author | Natasha Alexander Ilana Viljoen Susan Lucas |
| author_facet | Natasha Alexander Ilana Viljoen Susan Lucas |
| author_sort | Natasha Alexander |
| collection | DOAJ |
| description | Background: Stereotactic breast biopsies have become the gold standard for tissue diagnosis in non-palpable, sonographically occult breast abnormalities seen on mammogram. Only limited data exist in South Africa on the correlation between imaging findings and stereotactic biopsy histology.
Objectives: To describe the mammographic findings and histological diagnosis in patients who underwent stereotactic breast biopsy at a referral hospital. In addition, to evaluate the proportion of malignancy in each Breast Imaging Reporting and Data System (BI-RADS) category.
Method: A retrospective review of stereotactic breast biopsies was performed. Imaging characteristics (including BI-RADS category) and histological diagnosis were recorded. Using histopathology, cases were classified as benign, high-risk or malignant.
Results: A total of 131 biopsies, from 123 patients, were included in the study. Most biopsies were performed on asymptomatic patients (79.3%, 104/131). The majority were categorised as BI-RADS 4 and demonstrated calcifications. Histology revealed a malignant diagnosis in 40 (30.5%) patients, a high-risk lesion in 8 (6.1%) patients and a benign diagnosis in 83 (63.4%) patients. There was a stepwise increase in the proportion of malignancy from BI-RADS category 3 to 5. When compared with surgical histology, the stereotactic biopsies demonstrated an overall ductal carcinoma in situ (DCIS) underestimation rate of 10.3%.
Conclusion: Despite resource restrictions, stereotactic breast biopsies performed in a South African context produce radiological-pathological concordance in keeping with BI-RADS guidelines, as well as with local and international studies. |
| first_indexed | 2024-04-12T05:07:21Z |
| format | Article |
| id | doaj.art-c256dd68a0844a489895abfef7278776 |
| institution | Directory Open Access Journal |
| issn | 1027-202X 2078-6778 |
| language | English |
| last_indexed | 2024-04-12T05:07:21Z |
| publishDate | 2022-08-01 |
| publisher | AOSIS |
| record_format | Article |
| series | South African Journal of Radiology |
| spelling | doaj.art-c256dd68a0844a489895abfef72787762022-12-22T03:46:51ZengAOSISSouth African Journal of Radiology1027-202X2078-67782022-08-01261e1e910.4102/sajr.v26i1.24631199Stereotactic breast biopsies: Radiological-pathological concordance in a South African referral unitNatasha Alexander0Ilana Viljoen1Susan Lucas2Department of Radiology, Faculty of Radiation Sciences, University of the Witwatersrand, JohannesburgDepartment of Radiology, Faculty of Radiation Sciences, University of the Witwatersrand, JohannesburgDepartment of Radiology, Faculty of Radiation Sciences, University of the Witwatersrand, JohannesburgBackground: Stereotactic breast biopsies have become the gold standard for tissue diagnosis in non-palpable, sonographically occult breast abnormalities seen on mammogram. Only limited data exist in South Africa on the correlation between imaging findings and stereotactic biopsy histology. Objectives: To describe the mammographic findings and histological diagnosis in patients who underwent stereotactic breast biopsy at a referral hospital. In addition, to evaluate the proportion of malignancy in each Breast Imaging Reporting and Data System (BI-RADS) category. Method: A retrospective review of stereotactic breast biopsies was performed. Imaging characteristics (including BI-RADS category) and histological diagnosis were recorded. Using histopathology, cases were classified as benign, high-risk or malignant. Results: A total of 131 biopsies, from 123 patients, were included in the study. Most biopsies were performed on asymptomatic patients (79.3%, 104/131). The majority were categorised as BI-RADS 4 and demonstrated calcifications. Histology revealed a malignant diagnosis in 40 (30.5%) patients, a high-risk lesion in 8 (6.1%) patients and a benign diagnosis in 83 (63.4%) patients. There was a stepwise increase in the proportion of malignancy from BI-RADS category 3 to 5. When compared with surgical histology, the stereotactic biopsies demonstrated an overall ductal carcinoma in situ (DCIS) underestimation rate of 10.3%. Conclusion: Despite resource restrictions, stereotactic breast biopsies performed in a South African context produce radiological-pathological concordance in keeping with BI-RADS guidelines, as well as with local and international studies.https://sajr.org.za/index.php/sajr/article/view/2463stereotactic breast biopsybi-radsbreast cancerdigital breast tomosynthesisradiological-pathological concordance |
| spellingShingle | Natasha Alexander Ilana Viljoen Susan Lucas Stereotactic breast biopsies: Radiological-pathological concordance in a South African referral unit South African Journal of Radiology stereotactic breast biopsy bi-rads breast cancer digital breast tomosynthesis radiological-pathological concordance |
| title | Stereotactic breast biopsies: Radiological-pathological concordance in a South African referral unit |
| title_full | Stereotactic breast biopsies: Radiological-pathological concordance in a South African referral unit |
| title_fullStr | Stereotactic breast biopsies: Radiological-pathological concordance in a South African referral unit |
| title_full_unstemmed | Stereotactic breast biopsies: Radiological-pathological concordance in a South African referral unit |
| title_short | Stereotactic breast biopsies: Radiological-pathological concordance in a South African referral unit |
| title_sort | stereotactic breast biopsies radiological pathological concordance in a south african referral unit |
| topic | stereotactic breast biopsy bi-rads breast cancer digital breast tomosynthesis radiological-pathological concordance |
| url | https://sajr.org.za/index.php/sajr/article/view/2463 |
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