Methylation and transcriptome analysis reveal lung adenocarcinoma-specific diagnostic biomarkers

Methylation and transcriptome analysis reveal lung adenocarcinoma-specific diagnostic biomarkers

Abstract Background DNA methylation can regulate the role of long noncoding RNAs (lncRNAs) in the development of lung adenocarcinoma (LUAD). The present study aimed to identify methylation-driven lncRNAs and mRNAs as biomarkers in the prognosis of LUAD using bioinformatics analysis. Methods Differen...

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Bibliographic Details
Main Authors: Rui Li, Yi-E Yang, Yun-Hong Yin, Meng-Yu Zhang, Hao Li, Yi-Qing Qu
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Journal of Translational Medicine
Subjects:
Lung adenocarcinoma
Methylation-driven lncRNA
Methylation-driven mRNA
Biomarkers
Overall survival rate
Online Access:http://link.springer.com/article/10.1186/s12967-019-2068-z

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