Unlocking the potential of novel RTS, S/AS01, and R21/Matrix‐M™ malaria vaccines in African nations
Abstract Introduction Mass malaria vaccination, rather than vaccinating only children below age 5, has been proven to have the potential to reduce morbidity and mortality among those vaccinated, both young and old. Addressing vaccine scepticism and misinformation is crucial in African nations to bui...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Health Science Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/hsr2.1797 |
| _version_ | 1797331721901834240 |
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| author | Malik Olatunde Oduoye Muhammad Usman Haider Mohammed Dheyaa Marsool Marsool Mayowa Odunayo Kareem Adenike Ebunoluwa Adedayo Abdulkarim Surajo Abdulkarim Abdullahi Adeyemi Adegoke Ikshwaki Kaushik Hamza Irfan Hassan Abdullahi Yusuf Hussain Haider Shah Karim Arif Karim |
| author_facet | Malik Olatunde Oduoye Muhammad Usman Haider Mohammed Dheyaa Marsool Marsool Mayowa Odunayo Kareem Adenike Ebunoluwa Adedayo Abdulkarim Surajo Abdulkarim Abdullahi Adeyemi Adegoke Ikshwaki Kaushik Hamza Irfan Hassan Abdullahi Yusuf Hussain Haider Shah Karim Arif Karim |
| author_sort | Malik Olatunde Oduoye |
| collection | DOAJ |
| description | Abstract Introduction Mass malaria vaccination, rather than vaccinating only children below age 5, has been proven to have the potential to reduce morbidity and mortality among those vaccinated, both young and old. Addressing vaccine scepticism and misinformation is crucial in African nations to build public trust in malaria prevention. Therefore, including a wider range of demographics in vaccine trials is necessary for equitable representation and achieving herd immunity against malaria. Aim This present article aims to identify some of the obstacles that impede malaria vaccination usage and acceptability in African Nations in combating malaria in the region as it continues to pose a significant global public health problem. Methodology A literature search was done on the Malaria vaccine between 2000 and 2023. Past and present articles/studies on this topic were consulted on PubMed, Google Scholar, Scopus and Web of Science using the following keywords; “Malaria,” “Vaccines,” “African Nations,” “Obstacles, Strategies,” and “Public Health.” Results The recently approved RTS, S/AS01, and R21/Matrix‐M™ Malaria vaccines have the potential to prevent numerous deaths and cases of Malaria in Africa. These vaccines Malaria vaccines are cost‐effective in African areas with moderate to high plasmodium falciparum and can be delivered through routine immunization. Conclusion To combat malaria effectively in African Nations, African leaders need to set up a comprehensive approach that involves; prevention, healthcare access, implementation research strategies towards adoption and acceptance of malaria vaccines in Africa as well as community engagement with the religious leaders, the market women, community heads, schools, as well as students’ union towards the willingness and acceptability of the malaria vaccines among the African populations. |
| first_indexed | 2024-03-08T07:38:27Z |
| format | Article |
| id | doaj.art-c2595d0ea1eb4c9187b9c1777af8898f |
| institution | Directory Open Access Journal |
| issn | 2398-8835 |
| language | English |
| last_indexed | 2024-03-08T07:38:27Z |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Health Science Reports |
| spelling | doaj.art-c2595d0ea1eb4c9187b9c1777af8898f2024-02-02T18:04:59ZengWileyHealth Science Reports2398-88352024-01-0171n/an/a10.1002/hsr2.1797Unlocking the potential of novel RTS, S/AS01, and R21/Matrix‐M™ malaria vaccines in African nationsMalik Olatunde Oduoye0Muhammad Usman Haider1Mohammed Dheyaa Marsool Marsool2Mayowa Odunayo Kareem3Adenike Ebunoluwa Adedayo4Abdulkarim Surajo Abdulkarim5Abdullahi Adeyemi Adegoke6Ikshwaki Kaushik7Hamza Irfan8Hassan Abdullahi Yusuf9Hussain Haider Shah10Karim Arif Karim11Department of Medical Education/Research Medical Research Circle (MedReC) Bukavu CongoDepartment of Internal Medicine, Mayo Hospital Lahore King Edward Medical University Lahore Lahore PakistanDepartment of Internal Medicine, Al‐Kindy College of Medicine University of Baghdad Baghdad IraqDepartment of Internal Medicine Babcock University Teaching Hospital Ilishan‐Remo Ogun State NigeriaDepartment of Internal Medicine University of Debrecen Debrecen HungaryDepartment of Medicine and Surgery, College of Health Sciences Bayero University Kano Kano State NigeriaDepartment of Pharmacognosy University of Ibadan Ibadan Oyo State NigeriaDepartment of Medicine David Tvildiani Medical University Tbilisi GeorgiaDepartment of Medicine Shaikh Khalifa Bin Zayed Al Nahyan Medical and Dental College Lahore Lahore PakistanDepartment of Medicine and Surgery, College of Health Sciences Bayero University Kano Kano State NigeriaDepartment of Medicine Dow University of Health Sciences Karachi PakistanDepartment of Research and Ethics Kamuzu University of Health Sciences Blantyre MalawiAbstract Introduction Mass malaria vaccination, rather than vaccinating only children below age 5, has been proven to have the potential to reduce morbidity and mortality among those vaccinated, both young and old. Addressing vaccine scepticism and misinformation is crucial in African nations to build public trust in malaria prevention. Therefore, including a wider range of demographics in vaccine trials is necessary for equitable representation and achieving herd immunity against malaria. Aim This present article aims to identify some of the obstacles that impede malaria vaccination usage and acceptability in African Nations in combating malaria in the region as it continues to pose a significant global public health problem. Methodology A literature search was done on the Malaria vaccine between 2000 and 2023. Past and present articles/studies on this topic were consulted on PubMed, Google Scholar, Scopus and Web of Science using the following keywords; “Malaria,” “Vaccines,” “African Nations,” “Obstacles, Strategies,” and “Public Health.” Results The recently approved RTS, S/AS01, and R21/Matrix‐M™ Malaria vaccines have the potential to prevent numerous deaths and cases of Malaria in Africa. These vaccines Malaria vaccines are cost‐effective in African areas with moderate to high plasmodium falciparum and can be delivered through routine immunization. Conclusion To combat malaria effectively in African Nations, African leaders need to set up a comprehensive approach that involves; prevention, healthcare access, implementation research strategies towards adoption and acceptance of malaria vaccines in Africa as well as community engagement with the religious leaders, the market women, community heads, schools, as well as students’ union towards the willingness and acceptability of the malaria vaccines among the African populations.https://doi.org/10.1002/hsr2.1797African Nationsmalariaobstaclespublic healthstrategiesvaccines |
| spellingShingle | Malik Olatunde Oduoye Muhammad Usman Haider Mohammed Dheyaa Marsool Marsool Mayowa Odunayo Kareem Adenike Ebunoluwa Adedayo Abdulkarim Surajo Abdulkarim Abdullahi Adeyemi Adegoke Ikshwaki Kaushik Hamza Irfan Hassan Abdullahi Yusuf Hussain Haider Shah Karim Arif Karim Unlocking the potential of novel RTS, S/AS01, and R21/Matrix‐M™ malaria vaccines in African nations Health Science Reports African Nations malaria obstacles public health strategies vaccines |
| title | Unlocking the potential of novel RTS, S/AS01, and R21/Matrix‐M™ malaria vaccines in African nations |
| title_full | Unlocking the potential of novel RTS, S/AS01, and R21/Matrix‐M™ malaria vaccines in African nations |
| title_fullStr | Unlocking the potential of novel RTS, S/AS01, and R21/Matrix‐M™ malaria vaccines in African nations |
| title_full_unstemmed | Unlocking the potential of novel RTS, S/AS01, and R21/Matrix‐M™ malaria vaccines in African nations |
| title_short | Unlocking the potential of novel RTS, S/AS01, and R21/Matrix‐M™ malaria vaccines in African nations |
| title_sort | unlocking the potential of novel rts s as01 and r21 matrix m™ malaria vaccines in african nations |
| topic | African Nations malaria obstacles public health strategies vaccines |
| url | https://doi.org/10.1002/hsr2.1797 |
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