Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection
We present a case of immune thrombocytopenia (ITP) induced by the chimpanzee adenovirus-vectored vaccine, without evidence of thrombosis, eight days after vaccine administration. The thrombocytopenia condition improved after administering steroid treatment. This adenovirus vaccine had been reported...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-12-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/9/12/1486 |
| _version_ | 1797500063407144960 |
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| author | Po-Wei Liao Chieh-Lin Jerry Teng Cheng-Wei Chou |
| author_facet | Po-Wei Liao Chieh-Lin Jerry Teng Cheng-Wei Chou |
| author_sort | Po-Wei Liao |
| collection | DOAJ |
| description | We present a case of immune thrombocytopenia (ITP) induced by the chimpanzee adenovirus-vectored vaccine, without evidence of thrombosis, eight days after vaccine administration. The thrombocytopenia condition improved after administering steroid treatment. This adenovirus vaccine had been reported to induce rare side effects, such as immune thrombotic thrombocytopenia. This case report showed that it could also induce immune thrombocytopenia without the presence of thrombosis. Therefore, we should be cautious of this rare side effect as global vaccine administrations against coronavirus disease increase. |
| first_indexed | 2024-03-10T03:56:27Z |
| format | Article |
| id | doaj.art-c25c92a6f8e743cf80d5b3b46fee684f |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-10T03:56:27Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-c25c92a6f8e743cf80d5b3b46fee684f2023-11-23T10:55:01ZengMDPI AGVaccines2076-393X2021-12-01912148610.3390/vaccines9121486Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 InfectionPo-Wei Liao0Chieh-Lin Jerry Teng1Cheng-Wei Chou2Department of Internal Medicine, Division of Hematology/Medical Oncology, Taichung Veterans General Hospital, Taichung 40705, TaiwanDepartment of Internal Medicine, Division of Hematology/Medical Oncology, Taichung Veterans General Hospital, Taichung 40705, TaiwanDepartment of Internal Medicine, Division of Hematology/Medical Oncology, Taichung Veterans General Hospital, Taichung 40705, TaiwanWe present a case of immune thrombocytopenia (ITP) induced by the chimpanzee adenovirus-vectored vaccine, without evidence of thrombosis, eight days after vaccine administration. The thrombocytopenia condition improved after administering steroid treatment. This adenovirus vaccine had been reported to induce rare side effects, such as immune thrombotic thrombocytopenia. This case report showed that it could also induce immune thrombocytopenia without the presence of thrombosis. Therefore, we should be cautious of this rare side effect as global vaccine administrations against coronavirus disease increase.https://www.mdpi.com/2076-393X/9/12/1486SARS-CoV-2immune thrombocytopeniaadenovirus vaccineischemic strokeCOVID-19 |
| spellingShingle | Po-Wei Liao Chieh-Lin Jerry Teng Cheng-Wei Chou Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection Vaccines SARS-CoV-2 immune thrombocytopenia adenovirus vaccine ischemic stroke COVID-19 |
| title | Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection |
| title_full | Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection |
| title_fullStr | Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection |
| title_full_unstemmed | Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection |
| title_short | Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection |
| title_sort | immune thrombocytopenia induced by the chimpanzee adenovirus vectored vaccine against sars cov 2 infection |
| topic | SARS-CoV-2 immune thrombocytopenia adenovirus vaccine ischemic stroke COVID-19 |
| url | https://www.mdpi.com/2076-393X/9/12/1486 |
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