Modern Approaches in the Morphological Diagnosis of Inflammatory Bowel Diseases

The purpose of the review: to summarize the main data of the literature and our own accumulated practical experience of everyday diagnosis of inflammatory bowel diseases (IBD) to better represent the morphological features and histological conclusions.Key points. The microscopic picture of IBD is of...

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Main Authors: A. S. Tertychnyy, Kh. M. Akhriyeva, E. A. Kogan, O. V. Zayratyants, L. S. Selivanova
Format: Article
Language:Russian
Published: Gastro LLC 2022-08-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Subjects:
Online Access:https://www.gastro-j.ru/jour/article/view/652
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author A. S. Tertychnyy
Kh. M. Akhriyeva
E. A. Kogan
O. V. Zayratyants
L. S. Selivanova
author_facet A. S. Tertychnyy
Kh. M. Akhriyeva
E. A. Kogan
O. V. Zayratyants
L. S. Selivanova
author_sort A. S. Tertychnyy
collection DOAJ
description The purpose of the review: to summarize the main data of the literature and our own accumulated practical experience of everyday diagnosis of inflammatory bowel diseases (IBD) to better represent the morphological features and histological conclusions.Key points. The microscopic picture of IBD is often represented by a combination of basic histological characteristics that can be detected in other diseases and only in rare cases can be considered pathognomonic. No single histological feature can be used in isolation to diagnose ulcerative colitis or Crohn’s disease. Diagnostic accuracy is improved if several signs are taken into account at once, if changes within one or more parts of the intestine are analyzed, it is necessary to compare the identified changes with the clinical picture of the disease.Conclusion. The presented stages of the morphological study of biopsy specimens in patients with IBD and the exact characteristics of the detected changes will help to increase the diagnostic value of the study of ileo- and colonobiopsies, as well as improve mutual understanding between gastroenterologists and pathologists and, as a result of interaction between specialists, will increase the accuracy of the diagnosis.
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spelling doaj.art-c25ca40796b5414aaddcd46b84a8e1992024-03-25T16:53:10ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732022-08-01322738410.22416/1382-4376-2022-32-2-73-84475Modern Approaches in the Morphological Diagnosis of Inflammatory Bowel DiseasesA. S. Tertychnyy0Kh. M. Akhriyeva1E. A. Kogan2O. V. Zayratyants3L. S. Selivanova4Sechenov First Moscow State University (Sechenov University)Ingush State UniversitySechenov First Moscow State University (Sechenov University)A.I. Yevdokimov Moscow State University of Medicine and DentistryNational Medical Research Center for EndocrinologyThe purpose of the review: to summarize the main data of the literature and our own accumulated practical experience of everyday diagnosis of inflammatory bowel diseases (IBD) to better represent the morphological features and histological conclusions.Key points. The microscopic picture of IBD is often represented by a combination of basic histological characteristics that can be detected in other diseases and only in rare cases can be considered pathognomonic. No single histological feature can be used in isolation to diagnose ulcerative colitis or Crohn’s disease. Diagnostic accuracy is improved if several signs are taken into account at once, if changes within one or more parts of the intestine are analyzed, it is necessary to compare the identified changes with the clinical picture of the disease.Conclusion. The presented stages of the morphological study of biopsy specimens in patients with IBD and the exact characteristics of the detected changes will help to increase the diagnostic value of the study of ileo- and colonobiopsies, as well as improve mutual understanding between gastroenterologists and pathologists and, as a result of interaction between specialists, will increase the accuracy of the diagnosis.https://www.gastro-j.ru/jour/article/view/652inflammatory bowel diseaseulcerative colitiscrohn’s diseasepathological diagnostics
spellingShingle A. S. Tertychnyy
Kh. M. Akhriyeva
E. A. Kogan
O. V. Zayratyants
L. S. Selivanova
Modern Approaches in the Morphological Diagnosis of Inflammatory Bowel Diseases
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
inflammatory bowel disease
ulcerative colitis
crohn’s disease
pathological diagnostics
title Modern Approaches in the Morphological Diagnosis of Inflammatory Bowel Diseases
title_full Modern Approaches in the Morphological Diagnosis of Inflammatory Bowel Diseases
title_fullStr Modern Approaches in the Morphological Diagnosis of Inflammatory Bowel Diseases
title_full_unstemmed Modern Approaches in the Morphological Diagnosis of Inflammatory Bowel Diseases
title_short Modern Approaches in the Morphological Diagnosis of Inflammatory Bowel Diseases
title_sort modern approaches in the morphological diagnosis of inflammatory bowel diseases
topic inflammatory bowel disease
ulcerative colitis
crohn’s disease
pathological diagnostics
url https://www.gastro-j.ru/jour/article/view/652
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AT ovzayratyants modernapproachesinthemorphologicaldiagnosisofinflammatoryboweldiseases
AT lsselivanova modernapproachesinthemorphologicaldiagnosisofinflammatoryboweldiseases