Third Epidemiological Analysis of Nasopharyngeal Carcinoma in the Central Region of Japan from 2006 to 2015
The present study aimed to clarify the incidence and clinical outcomes of nasopharyngeal carcinoma (NPC) in the Chubu region of Japan from 2006 to 2015, compared with previous reports. A retrospective analysis was conducted based on medical records from 40 hospitals located in the Chubu region in th...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-08-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/11/8/1180 |
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| author | Masafumi Kanno Norihiko Narita Yasushi Fujimoto Naohiro Wakisaka Tomokazu Yoshizaki Takeshi Kodaira Chiyoko Makita Yuichiro Sato Keisuke Yamazaki Takanori Wakaoka Yuzo Shimode Hiroyuki Tsuji Ryosuke Kito Hajime Ishinaga Seiji Hosokawa Hiromasa Takakura Kunihiro Nishimura Takuma Matoba Shigeharu Fujieda |
| author_facet | Masafumi Kanno Norihiko Narita Yasushi Fujimoto Naohiro Wakisaka Tomokazu Yoshizaki Takeshi Kodaira Chiyoko Makita Yuichiro Sato Keisuke Yamazaki Takanori Wakaoka Yuzo Shimode Hiroyuki Tsuji Ryosuke Kito Hajime Ishinaga Seiji Hosokawa Hiromasa Takakura Kunihiro Nishimura Takuma Matoba Shigeharu Fujieda |
| author_sort | Masafumi Kanno |
| collection | DOAJ |
| description | The present study aimed to clarify the incidence and clinical outcomes of nasopharyngeal carcinoma (NPC) in the Chubu region of Japan from 2006 to 2015, compared with previous reports. A retrospective analysis was conducted based on medical records from 40 hospitals located in the Chubu region in the central Japanese main island, with a population of around 22.66 million individuals. This study was designed in line with to two previous clinical studies into NPC conducted in the same area of Japan. We recruited NPC patients diagnosed in hospitals across this area over a 10-year period (2006−2015) using a questionnaire about sex, age, primary site, clinical symptoms, pathology, Union for International Cancer Control (UICC) staging, serological exam, treatment, and survival. A total of 620 NPC patients were identified. The age-standardized incidence of NPC from 2006 to 2015 was 0.27 per 100,000 individuals per year. There were no significant differences between this study and the previous two studies conducted in the same area of Japan. The five-year overall survival rate for all patients was 75.9%, while those for patients with stages I, II, III, and IVA were 97%, 91%, 79%, and 68%, respectively. The age-standardized annual incidence of NPC in the present study was 0.27 per 100,000 individuals per year, which was relatively low and stable. The five-year overall survival rate for all NPC patients was significantly improved in this decade compared with previous studies. The smoking rates in male and female NPC patients were 64.5% and 18.8%, respectively, thereby suggesting the involvement of smoking in the incidence of NPC. |
| first_indexed | 2024-03-12T07:13:34Z |
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| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-12T07:13:34Z |
| publishDate | 2019-08-01 |
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| series | Cancers |
| spelling | doaj.art-c25e91fc93534b97861459a11383fb1d2023-09-02T22:57:07ZengMDPI AGCancers2072-66942019-08-01118118010.3390/cancers11081180cancers11081180Third Epidemiological Analysis of Nasopharyngeal Carcinoma in the Central Region of Japan from 2006 to 2015Masafumi Kanno0Norihiko Narita1Yasushi Fujimoto2Naohiro Wakisaka3Tomokazu Yoshizaki4Takeshi Kodaira5Chiyoko Makita6Yuichiro Sato7Keisuke Yamazaki8Takanori Wakaoka9Yuzo Shimode10Hiroyuki Tsuji11Ryosuke Kito12Hajime Ishinaga13Seiji Hosokawa14Hiromasa Takakura15Kunihiro Nishimura16Takuma Matoba17Shigeharu Fujieda18Department of Otorhinolaryngology Head and Neck Surgery Graduate School of Medical Science University of Fukui, Fukui 910-1193, JapanDepartment of Otorhinolaryngology Head and Neck Surgery Graduate School of Medical Science University of Fukui, Fukui 910-1193, JapanOtorhinolaryngology/Cognitive and Speech Medicine Nagoya University Graduate School of Medicine, Nagoya University, Aichi 466-8550, JapanDepartment of Otolaryngology, Head and Neck Surgery Graduate School of Medical Science Kanazawa University, Ishikawa 920-8641, JapanDepartment of Otolaryngology, Head and Neck Surgery Graduate School of Medical Science Kanazawa University, Ishikawa 920-8641, JapanDepartment of Radiation Oncology Aichi Cancer Center, Aichi 464-8681, JapanDepartment of Radiation Oncology Aichi Cancer Center, Aichi 464-8681, JapanDepartment of Head and Neck Surgery, Niigata Cancer Center Hospital, Niigata 951-8566, JapanDepartments of Otolaryngology Head and Neck Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8520, JapanDepartment of Otolaryngology, Gifu University Graduate School of Medicine, Gifu 501-1194, JapanDepartment of Head and Neck Surgery, Kanazawa Medical University, Ishikawa 920-0293, JapanDepartment of Head and Neck Surgery, Kanazawa Medical University, Ishikawa 920-0293, JapanDepartment of Otolaryngology, Shinshu University School of Medicine, Nagano 390-8621, JapanDepartment of Otorhinolaryngology Head and Neck Surgery, Mie University Graduate School of Medicine, Mie 514-8507, JapanDepartment of Otorhinolaryngology Head and Neck Surgery, Hamamatsu University School of Medicine, Shizuoka 431-3192, JapanDepartment of Otorhinolaryngology, Head and Neck Surgery, University of Toyama, Toyama 930-0194, JapanDepartment of Otorhinolaryngology, Aichi Medical University School of Medicine, Aichi 480-1195, JapanDepartment of Otorhinolaryngology and Head and neck surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8602, JapanDepartment of Otorhinolaryngology Head and Neck Surgery Graduate School of Medical Science University of Fukui, Fukui 910-1193, JapanThe present study aimed to clarify the incidence and clinical outcomes of nasopharyngeal carcinoma (NPC) in the Chubu region of Japan from 2006 to 2015, compared with previous reports. A retrospective analysis was conducted based on medical records from 40 hospitals located in the Chubu region in the central Japanese main island, with a population of around 22.66 million individuals. This study was designed in line with to two previous clinical studies into NPC conducted in the same area of Japan. We recruited NPC patients diagnosed in hospitals across this area over a 10-year period (2006−2015) using a questionnaire about sex, age, primary site, clinical symptoms, pathology, Union for International Cancer Control (UICC) staging, serological exam, treatment, and survival. A total of 620 NPC patients were identified. The age-standardized incidence of NPC from 2006 to 2015 was 0.27 per 100,000 individuals per year. There were no significant differences between this study and the previous two studies conducted in the same area of Japan. The five-year overall survival rate for all patients was 75.9%, while those for patients with stages I, II, III, and IVA were 97%, 91%, 79%, and 68%, respectively. The age-standardized annual incidence of NPC in the present study was 0.27 per 100,000 individuals per year, which was relatively low and stable. The five-year overall survival rate for all NPC patients was significantly improved in this decade compared with previous studies. The smoking rates in male and female NPC patients were 64.5% and 18.8%, respectively, thereby suggesting the involvement of smoking in the incidence of NPC.https://www.mdpi.com/2072-6694/11/8/1180nasopharyngeal carcinoma (NPC)Japanincidencesurvival |
| spellingShingle | Masafumi Kanno Norihiko Narita Yasushi Fujimoto Naohiro Wakisaka Tomokazu Yoshizaki Takeshi Kodaira Chiyoko Makita Yuichiro Sato Keisuke Yamazaki Takanori Wakaoka Yuzo Shimode Hiroyuki Tsuji Ryosuke Kito Hajime Ishinaga Seiji Hosokawa Hiromasa Takakura Kunihiro Nishimura Takuma Matoba Shigeharu Fujieda Third Epidemiological Analysis of Nasopharyngeal Carcinoma in the Central Region of Japan from 2006 to 2015 Cancers nasopharyngeal carcinoma (NPC) Japan incidence survival |
| title | Third Epidemiological Analysis of Nasopharyngeal Carcinoma in the Central Region of Japan from 2006 to 2015 |
| title_full | Third Epidemiological Analysis of Nasopharyngeal Carcinoma in the Central Region of Japan from 2006 to 2015 |
| title_fullStr | Third Epidemiological Analysis of Nasopharyngeal Carcinoma in the Central Region of Japan from 2006 to 2015 |
| title_full_unstemmed | Third Epidemiological Analysis of Nasopharyngeal Carcinoma in the Central Region of Japan from 2006 to 2015 |
| title_short | Third Epidemiological Analysis of Nasopharyngeal Carcinoma in the Central Region of Japan from 2006 to 2015 |
| title_sort | third epidemiological analysis of nasopharyngeal carcinoma in the central region of japan from 2006 to 2015 |
| topic | nasopharyngeal carcinoma (NPC) Japan incidence survival |
| url | https://www.mdpi.com/2072-6694/11/8/1180 |
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