An Antibiotic Nanobomb Constructed from pH‐Responsive Chemical Bonds in Metal‐Phenolic Network Nanoparticles for Biofilm Eradication and Corneal Ulcer Healing

An Antibiotic Nanobomb Constructed from pH‐Responsive Chemical Bonds in Metal‐Phenolic Network Nanoparticles for Biofilm Eradication and Corneal Ulcer Healing

Abstract In the treatment of refractory corneal ulcers caused by Pseudomonas aeruginosa, antibacterial drugs delivery faces the drawbacks of low permeability and short ocular surface retention time. Hence, novel positively‐charged modular nanoparticles (NPs) are developed to load tobramycin (TOB) th...

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Bibliographic Details
Main Authors: Qiang Gao, Xiaoying Chu, Jie Yang, Yishun Guo, Hanwen Guo, Siyuan Qian, Ying‐Wei Yang, Bailiang Wang
Format: Article
Language:English
Published: Wiley 2024-06-01
Series:Advanced Science
Subjects:
antibacterial
corneal ulcers
metal‐phenolic network
modular assembly
pH responsiveness
Online Access:https://doi.org/10.1002/advs.202309086

Internet

https://doi.org/10.1002/advs.202309086

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