Structural Determinants and Their Role in Cyanobacterial Morphogenesis
Cells have to erect and sustain an organized and dynamically adaptable structure for an efficient mode of operation that allows drastic morphological changes during cell growth and cell division. These manifold tasks are complied by the so-called cytoskeleton and its associated proteins. In bacteria...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-12-01
|
| Series: | Life |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-1729/10/12/355 |
| _version_ | 1797544366037794816 |
|---|---|
| author | Benjamin L. Springstein Dennis J. Nürnberg Gregor L. Weiss Martin Pilhofer Karina Stucken |
| author_facet | Benjamin L. Springstein Dennis J. Nürnberg Gregor L. Weiss Martin Pilhofer Karina Stucken |
| author_sort | Benjamin L. Springstein |
| collection | DOAJ |
| description | Cells have to erect and sustain an organized and dynamically adaptable structure for an efficient mode of operation that allows drastic morphological changes during cell growth and cell division. These manifold tasks are complied by the so-called cytoskeleton and its associated proteins. In bacteria, FtsZ and MreB, the bacterial homologs to tubulin and actin, respectively, as well as coiled-coil-rich proteins of intermediate filament (IF)-like function to fulfil these tasks. Despite generally being characterized as Gram-negative, cyanobacteria have a remarkably thick peptidoglycan layer and possess Gram-positive-specific cell division proteins such as SepF and DivIVA-like proteins, besides Gram-negative and cyanobacterial-specific cell division proteins like MinE, SepI, ZipN (Ftn2) and ZipS (Ftn6). The diversity of cellular morphologies and cell growth strategies in cyanobacteria could therefore be the result of additional unidentified structural determinants such as cytoskeletal proteins. In this article, we review the current advances in the understanding of the cyanobacterial cell shape, cell division and cell growth. |
| first_indexed | 2024-03-10T13:59:26Z |
| format | Article |
| id | doaj.art-c261c2f3882b4a8fa737b36241b1c6f7 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-10T13:59:26Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-c261c2f3882b4a8fa737b36241b1c6f72023-11-21T01:21:58ZengMDPI AGLife2075-17292020-12-01101235510.3390/life10120355Structural Determinants and Their Role in Cyanobacterial MorphogenesisBenjamin L. Springstein0Dennis J. Nürnberg1Gregor L. Weiss2Martin Pilhofer3Karina Stucken4Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USADepartment of Physics, Biophysics and Biochemistry of Photosynthetic Organisms, Freie Universität Berlin, 14195 Berlin, GermanyDepartment of Biology, Institute of Molecular Biology & Biophysics, ETH Zürich, 8092 Zürich, SwitzerlandDepartment of Biology, Institute of Molecular Biology & Biophysics, ETH Zürich, 8092 Zürich, SwitzerlandDepartment of Food Engineering, Universidad de La Serena, La Serena 1720010, ChileCells have to erect and sustain an organized and dynamically adaptable structure for an efficient mode of operation that allows drastic morphological changes during cell growth and cell division. These manifold tasks are complied by the so-called cytoskeleton and its associated proteins. In bacteria, FtsZ and MreB, the bacterial homologs to tubulin and actin, respectively, as well as coiled-coil-rich proteins of intermediate filament (IF)-like function to fulfil these tasks. Despite generally being characterized as Gram-negative, cyanobacteria have a remarkably thick peptidoglycan layer and possess Gram-positive-specific cell division proteins such as SepF and DivIVA-like proteins, besides Gram-negative and cyanobacterial-specific cell division proteins like MinE, SepI, ZipN (Ftn2) and ZipS (Ftn6). The diversity of cellular morphologies and cell growth strategies in cyanobacteria could therefore be the result of additional unidentified structural determinants such as cytoskeletal proteins. In this article, we review the current advances in the understanding of the cyanobacterial cell shape, cell division and cell growth.https://www.mdpi.com/2075-1729/10/12/355cyanobacteriamorphologycell divisioncell shapecytoskeletonFtsZ |
| spellingShingle | Benjamin L. Springstein Dennis J. Nürnberg Gregor L. Weiss Martin Pilhofer Karina Stucken Structural Determinants and Their Role in Cyanobacterial Morphogenesis Life cyanobacteria morphology cell division cell shape cytoskeleton FtsZ |
| title | Structural Determinants and Their Role in Cyanobacterial Morphogenesis |
| title_full | Structural Determinants and Their Role in Cyanobacterial Morphogenesis |
| title_fullStr | Structural Determinants and Their Role in Cyanobacterial Morphogenesis |
| title_full_unstemmed | Structural Determinants and Their Role in Cyanobacterial Morphogenesis |
| title_short | Structural Determinants and Their Role in Cyanobacterial Morphogenesis |
| title_sort | structural determinants and their role in cyanobacterial morphogenesis |
| topic | cyanobacteria morphology cell division cell shape cytoskeleton FtsZ |
| url | https://www.mdpi.com/2075-1729/10/12/355 |
| work_keys_str_mv | AT benjaminlspringstein structuraldeterminantsandtheirroleincyanobacterialmorphogenesis AT dennisjnurnberg structuraldeterminantsandtheirroleincyanobacterialmorphogenesis AT gregorlweiss structuraldeterminantsandtheirroleincyanobacterialmorphogenesis AT martinpilhofer structuraldeterminantsandtheirroleincyanobacterialmorphogenesis AT karinastucken structuraldeterminantsandtheirroleincyanobacterialmorphogenesis |