Kawasaki disease complicated with shock syndrome, macrophage activation syndrome, and acute abdomen in children: Two case reports
BackgroundKawasaki disease (KD) is an acute systemic vasculitis that can involve multiple organs. Few reports have been published about KD patients presenting with multiple complications such as acute abdomen, KD shock syndrome (KDSS), and macrophage activation syndrome (MAS).Case DescriptionWe pres...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-04-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2023.1152242/full |
| _version_ | 1797843265532198912 |
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| author | Cong Yi Xiang She Jia Chen |
| author_facet | Cong Yi Xiang She Jia Chen |
| author_sort | Cong Yi |
| collection | DOAJ |
| description | BackgroundKawasaki disease (KD) is an acute systemic vasculitis that can involve multiple organs. Few reports have been published about KD patients presenting with multiple complications such as acute abdomen, KD shock syndrome (KDSS), and macrophage activation syndrome (MAS).Case DescriptionWe present the cases of two males (9 and 12 years old) diagnosed with KD accompanied by rare manifestations. Case 1 is a 9-year-old male treated for acute appendicitis, KDSS, and MAS. Case 2 is a 12-year-old male who presented with KDSS, MAS, and an ileal perforation. They were treated with intravenous immunoglobulin, aspirin, high-dose corticosteroids, vasoactive drugs, and symptomatic treatment, with good outcomes.ConclusionsClinicians should be aware of the possibility of KD in the presence of fever and unusual manifestations, such as severe inflammatory indicators and acute abdomen that is nonresponsive to antibiotic therapy. Meanwhile, KD-related unusual complications should be recognized, such as KDSS and MAS. |
| first_indexed | 2024-04-09T17:02:22Z |
| format | Article |
| id | doaj.art-c262ead3d40e4bf0a93fdb0ad052fce6 |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-09T17:02:22Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-c262ead3d40e4bf0a93fdb0ad052fce62023-04-21T04:32:44ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602023-04-011110.3389/fped.2023.11522421152242Kawasaki disease complicated with shock syndrome, macrophage activation syndrome, and acute abdomen in children: Two case reportsCong YiXiang SheJia ChenBackgroundKawasaki disease (KD) is an acute systemic vasculitis that can involve multiple organs. Few reports have been published about KD patients presenting with multiple complications such as acute abdomen, KD shock syndrome (KDSS), and macrophage activation syndrome (MAS).Case DescriptionWe present the cases of two males (9 and 12 years old) diagnosed with KD accompanied by rare manifestations. Case 1 is a 9-year-old male treated for acute appendicitis, KDSS, and MAS. Case 2 is a 12-year-old male who presented with KDSS, MAS, and an ileal perforation. They were treated with intravenous immunoglobulin, aspirin, high-dose corticosteroids, vasoactive drugs, and symptomatic treatment, with good outcomes.ConclusionsClinicians should be aware of the possibility of KD in the presence of fever and unusual manifestations, such as severe inflammatory indicators and acute abdomen that is nonresponsive to antibiotic therapy. Meanwhile, KD-related unusual complications should be recognized, such as KDSS and MAS.https://www.frontiersin.org/articles/10.3389/fped.2023.1152242/fullkawasaki diseasekawasaki disease shock syndromemacrophage activation syndromeacute abdomencase report |
| spellingShingle | Cong Yi Xiang She Jia Chen Kawasaki disease complicated with shock syndrome, macrophage activation syndrome, and acute abdomen in children: Two case reports Frontiers in Pediatrics kawasaki disease kawasaki disease shock syndrome macrophage activation syndrome acute abdomen case report |
| title | Kawasaki disease complicated with shock syndrome, macrophage activation syndrome, and acute abdomen in children: Two case reports |
| title_full | Kawasaki disease complicated with shock syndrome, macrophage activation syndrome, and acute abdomen in children: Two case reports |
| title_fullStr | Kawasaki disease complicated with shock syndrome, macrophage activation syndrome, and acute abdomen in children: Two case reports |
| title_full_unstemmed | Kawasaki disease complicated with shock syndrome, macrophage activation syndrome, and acute abdomen in children: Two case reports |
| title_short | Kawasaki disease complicated with shock syndrome, macrophage activation syndrome, and acute abdomen in children: Two case reports |
| title_sort | kawasaki disease complicated with shock syndrome macrophage activation syndrome and acute abdomen in children two case reports |
| topic | kawasaki disease kawasaki disease shock syndrome macrophage activation syndrome acute abdomen case report |
| url | https://www.frontiersin.org/articles/10.3389/fped.2023.1152242/full |
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