Tanshinone IIA protects motor neuron-like NSC-34 cells against lipopolysaccharide-induced cell injury by the regulation of the lncRNA TCTN2/miR-125a-5p/DUSP1 axis

Tanshinone IIA protects motor neuron-like NSC-34 cells against lipopolysaccharide-induced cell injury by the regulation of the lncRNA TCTN2/miR-125a-5p/DUSP1 axis

Background: Tanshinone IIA (TSIIA) exerts a protective role in spinal cord injury (SCI). However, the mechanism of TSIIA activity in SCI remains to be elucidated. Methods: Cell viability and apoptosis were gauged by CCK-8 assay and flow cytometry, respectively. The expression levels of lncRNA TCTN2,...

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Bibliographic Details
Main Authors: Qiwen Yan, Yajing Xun, Debao Lei, Hongyu Zhai
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Regenerative Therapy
Subjects:
Tanshinone IIA
TCTN2
miR-125a-5p
DUSP1
Cell injury
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320423000287

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