Partial Splenic Embolization for Hypersplenism Associated with Steatohepatitis in a Hemodialysis Patient
Hypersplenism (HS) is a disorder characterized by a triad of splenomegaly, peripheral cytopenia due to premature destruction of blood cells and normocellular bone marrow. Its etiology is diverse and includes (a) primary autoimmune cytopenias, (b) secondary to congestion due to portal hypertension in...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2021-01-01
|
| Series: | Saudi Journal of Kidney Diseases and Transplantation |
| Online Access: | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2021;volume=32;issue=1;spage=255;epage=260;aulast=El-Reshaid |
| _version_ | 1818668018877595648 |
|---|---|
| author | Kamel El-Reshaid Fahad Alabdulghani Shaikha Al-Bader |
| author_facet | Kamel El-Reshaid Fahad Alabdulghani Shaikha Al-Bader |
| author_sort | Kamel El-Reshaid |
| collection | DOAJ |
| description | Hypersplenism (HS) is a disorder characterized by a triad of splenomegaly, peripheral cytopenia due to premature destruction of blood cells and normocellular bone marrow. Its etiology is diverse and includes (a) primary autoimmune cytopenias, (b) secondary to congestion due to portal hypertension in cirrhosis and, other causes such asperiportal fibrosis, infections, autoimmune diseases, lymphoproliferative disorders, infiltrative diseases and hemolytic anemias. The latter diseases are common in patients with end-stage kidney disease. In severe cases, co-existence of multiple co-morbid conditions, coagulopathy of uremia and dialysis-anticoagulation, and their immunosuppressive state render surgical splenectomy at highrisk. Mid-segment partial splenic infarction and with an aim at 50%–70% splenic volume loss was shown to be a less invasive therapy for HS. In our case report, we describe its first successful trial in a hemodialysis patient with severe HS due to cirrhosis. |
| first_indexed | 2024-12-17T06:29:39Z |
| format | Article |
| id | doaj.art-c2668e66c5ed4616a38360c9f733028e |
| institution | Directory Open Access Journal |
| issn | 1319-2442 |
| language | English |
| last_indexed | 2024-12-17T06:29:39Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Kidney Diseases and Transplantation |
| spelling | doaj.art-c2668e66c5ed4616a38360c9f733028e2022-12-21T22:00:11ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422021-01-0132125526010.4103/1319-2442.318535Partial Splenic Embolization for Hypersplenism Associated with Steatohepatitis in a Hemodialysis PatientKamel El-ReshaidFahad AlabdulghaniShaikha Al-BaderHypersplenism (HS) is a disorder characterized by a triad of splenomegaly, peripheral cytopenia due to premature destruction of blood cells and normocellular bone marrow. Its etiology is diverse and includes (a) primary autoimmune cytopenias, (b) secondary to congestion due to portal hypertension in cirrhosis and, other causes such asperiportal fibrosis, infections, autoimmune diseases, lymphoproliferative disorders, infiltrative diseases and hemolytic anemias. The latter diseases are common in patients with end-stage kidney disease. In severe cases, co-existence of multiple co-morbid conditions, coagulopathy of uremia and dialysis-anticoagulation, and their immunosuppressive state render surgical splenectomy at highrisk. Mid-segment partial splenic infarction and with an aim at 50%–70% splenic volume loss was shown to be a less invasive therapy for HS. In our case report, we describe its first successful trial in a hemodialysis patient with severe HS due to cirrhosis.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2021;volume=32;issue=1;spage=255;epage=260;aulast=El-Reshaid |
| spellingShingle | Kamel El-Reshaid Fahad Alabdulghani Shaikha Al-Bader Partial Splenic Embolization for Hypersplenism Associated with Steatohepatitis in a Hemodialysis Patient Saudi Journal of Kidney Diseases and Transplantation |
| title | Partial Splenic Embolization for Hypersplenism Associated with Steatohepatitis in a Hemodialysis Patient |
| title_full | Partial Splenic Embolization for Hypersplenism Associated with Steatohepatitis in a Hemodialysis Patient |
| title_fullStr | Partial Splenic Embolization for Hypersplenism Associated with Steatohepatitis in a Hemodialysis Patient |
| title_full_unstemmed | Partial Splenic Embolization for Hypersplenism Associated with Steatohepatitis in a Hemodialysis Patient |
| title_short | Partial Splenic Embolization for Hypersplenism Associated with Steatohepatitis in a Hemodialysis Patient |
| title_sort | partial splenic embolization for hypersplenism associated with steatohepatitis in a hemodialysis patient |
| url | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2021;volume=32;issue=1;spage=255;epage=260;aulast=El-Reshaid |
| work_keys_str_mv | AT kamelelreshaid partialsplenicembolizationforhypersplenismassociatedwithsteatohepatitisinahemodialysispatient AT fahadalabdulghani partialsplenicembolizationforhypersplenismassociatedwithsteatohepatitisinahemodialysispatient AT shaikhaalbader partialsplenicembolizationforhypersplenismassociatedwithsteatohepatitisinahemodialysispatient |