Osteoma of the Jaw as First Clinical Sign of Gardner’s Syndrome: The Experience of Two Italian Centers and Review
Gardner’s syndrome (GS) is a combination of polyposis, osteomas, fibromas, and sebaceous cysts. The aim of the study is to highlight whether maxillofacial osteoma could represent an early detection symptom of GS. Patients with suspected osteoma of the jaw underwent genetic and radiographical examina...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/4/1496 |
| _version_ | 1797620218595377152 |
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| author | Silvia D’Agostino Fabio Dell’Olio Angela Tempesta Francesca Cervinara Antonio D’Amati Marco Dolci Gianfranco Favia Saverio Capodiferro Luisa Limongelli |
| author_facet | Silvia D’Agostino Fabio Dell’Olio Angela Tempesta Francesca Cervinara Antonio D’Amati Marco Dolci Gianfranco Favia Saverio Capodiferro Luisa Limongelli |
| author_sort | Silvia D’Agostino |
| collection | DOAJ |
| description | Gardner’s syndrome (GS) is a combination of polyposis, osteomas, fibromas, and sebaceous cysts. The aim of the study is to highlight whether maxillofacial osteoma could represent an early detection symptom of GS. Patients with suspected osteoma of the jaw underwent genetic and radiographical examinations. The database gathered 19 patients with oral osteoma that was histologically diagnosed; the whole sample was positive for APC gene mutation. Other cranial and peripheral locations were reported. Osteoma of the jaw is a crucial predictive factor of GS, and dentists and oral and maxillofacial surgeons must be aware of the importance of a timely diagnosis. |
| first_indexed | 2024-03-11T08:37:59Z |
| format | Article |
| id | doaj.art-c26c54b93fee43ab88ef61c9284c60e9 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T08:37:59Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-c26c54b93fee43ab88ef61c9284c60e92023-11-16T21:20:23ZengMDPI AGJournal of Clinical Medicine2077-03832023-02-01124149610.3390/jcm12041496Osteoma of the Jaw as First Clinical Sign of Gardner’s Syndrome: The Experience of Two Italian Centers and ReviewSilvia D’Agostino0Fabio Dell’Olio1Angela Tempesta2Francesca Cervinara3Antonio D’Amati4Marco Dolci5Gianfranco Favia6Saverio Capodiferro7Luisa Limongelli8Department of Medical, Oral, and Biotechnological Sciences, University G. d’Annunzio, 66100 Chieti, ItalyComplex Operating Unit of Odontostomatology, Department of Interdisciplinary Medicine, Aldo Moro University, 70121 Bari, ItalyComplex Operating Unit of Odontostomatology, Department of Interdisciplinary Medicine, Aldo Moro University, 70121 Bari, ItalyComplex Operating Unit of Odontostomatology, Department of Interdisciplinary Medicine, Aldo Moro University, 70121 Bari, ItalyOperating Unit of Pathological Anatomy, Department of Emergency and Organ Transplantation, Aldo Moro University, 70121 Bari, ItalyDepartment of Medical, Oral, and Biotechnological Sciences, University G. d’Annunzio, 66100 Chieti, ItalyComplex Operating Unit of Odontostomatology, Department of Interdisciplinary Medicine, Aldo Moro University, 70121 Bari, ItalyComplex Operating Unit of Odontostomatology, Department of Interdisciplinary Medicine, Aldo Moro University, 70121 Bari, ItalyComplex Operating Unit of Odontostomatology, Department of Interdisciplinary Medicine, Aldo Moro University, 70121 Bari, ItalyGardner’s syndrome (GS) is a combination of polyposis, osteomas, fibromas, and sebaceous cysts. The aim of the study is to highlight whether maxillofacial osteoma could represent an early detection symptom of GS. Patients with suspected osteoma of the jaw underwent genetic and radiographical examinations. The database gathered 19 patients with oral osteoma that was histologically diagnosed; the whole sample was positive for APC gene mutation. Other cranial and peripheral locations were reported. Osteoma of the jaw is a crucial predictive factor of GS, and dentists and oral and maxillofacial surgeons must be aware of the importance of a timely diagnosis.https://www.mdpi.com/2077-0383/12/4/1496Gardner’s syndromeosteomasfamilial adenomatous polyposisdesmoid tumorssupernumerary teeth |
| spellingShingle | Silvia D’Agostino Fabio Dell’Olio Angela Tempesta Francesca Cervinara Antonio D’Amati Marco Dolci Gianfranco Favia Saverio Capodiferro Luisa Limongelli Osteoma of the Jaw as First Clinical Sign of Gardner’s Syndrome: The Experience of Two Italian Centers and Review Journal of Clinical Medicine Gardner’s syndrome osteomas familial adenomatous polyposis desmoid tumors supernumerary teeth |
| title | Osteoma of the Jaw as First Clinical Sign of Gardner’s Syndrome: The Experience of Two Italian Centers and Review |
| title_full | Osteoma of the Jaw as First Clinical Sign of Gardner’s Syndrome: The Experience of Two Italian Centers and Review |
| title_fullStr | Osteoma of the Jaw as First Clinical Sign of Gardner’s Syndrome: The Experience of Two Italian Centers and Review |
| title_full_unstemmed | Osteoma of the Jaw as First Clinical Sign of Gardner’s Syndrome: The Experience of Two Italian Centers and Review |
| title_short | Osteoma of the Jaw as First Clinical Sign of Gardner’s Syndrome: The Experience of Two Italian Centers and Review |
| title_sort | osteoma of the jaw as first clinical sign of gardner s syndrome the experience of two italian centers and review |
| topic | Gardner’s syndrome osteomas familial adenomatous polyposis desmoid tumors supernumerary teeth |
| url | https://www.mdpi.com/2077-0383/12/4/1496 |
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