Potentially inappropriate medications among elderly Brazilian outpatients

CONTEXT AND OBJECTIVESIn Brazil, few studies have investigated the prevalence of potentially inappropriate medications (PIMs) among elderly outpatients. This study aimed to determine the prevalence of PIMs prescribed for elderly outpatients, identify the PIMs most commonly involved, and investigate...

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Main Authors: Christine Grützmann Faustino, Maria Cristina Guerra Passarelli, Wilson Jacob-Filho
Format: Article
Language:English
Published: Associação Paulista de Medicina
Series:São Paulo Medical Journal
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802013000100019&lng=en&tlng=en
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author Christine Grützmann Faustino
Maria Cristina Guerra Passarelli
Wilson Jacob-Filho
author_facet Christine Grützmann Faustino
Maria Cristina Guerra Passarelli
Wilson Jacob-Filho
author_sort Christine Grützmann Faustino
collection DOAJ
description CONTEXT AND OBJECTIVESIn Brazil, few studies have investigated the prevalence of potentially inappropriate medications (PIMs) among elderly outpatients. This study aimed to determine the prevalence of PIMs prescribed for elderly outpatients, identify the PIMs most commonly involved, and investigate whether age, sex and number of medications are related to prescription of such medications.DESIGN AND SETTINGObservational descriptive study developed in the Geriatrics Service of the Central Institute of Hospital das Clínicas (HC), Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, Brazil.METHODSPrescriptions issued to 1,270 elderly patients (≥ 60 years) were gathered from a database. These prescriptions had been written by geriatricians at a tertiary-level university hospital in São Paulo, Brazil, between February and May 2008. The prescriptions were divided according to sex and age group (60-69, 70-79 and ≥ 80). The Beers criteria were used to evaluate PIMs.RESULTSMost of the sample comprised women (77%) and the mean age was 80.1 years. The mean prevalence of PIM prescriptions was 26.9%. Female sex and number of medications prescribed were associated with prescription of PIMs. The chance of having a PIM prescription was lower among patients ≥ 70 years.CONCLUSIONThe greater prevalence of PIMs was correlated with female sex. The chance of having a PIM prescription was lower among patients ≥ 70 years and became greater with increasing numbers of medications prescribed (≥ 7).
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spelling doaj.art-c26fc85db40a4af29aecf39dae4410a52022-12-21T23:51:21ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-94601311192610.1590/S1516-31802013000100004S1516-31802013000100019Potentially inappropriate medications among elderly Brazilian outpatientsChristine Grützmann FaustinoMaria Cristina Guerra PassarelliWilson Jacob-FilhoCONTEXT AND OBJECTIVESIn Brazil, few studies have investigated the prevalence of potentially inappropriate medications (PIMs) among elderly outpatients. This study aimed to determine the prevalence of PIMs prescribed for elderly outpatients, identify the PIMs most commonly involved, and investigate whether age, sex and number of medications are related to prescription of such medications.DESIGN AND SETTINGObservational descriptive study developed in the Geriatrics Service of the Central Institute of Hospital das Clínicas (HC), Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, Brazil.METHODSPrescriptions issued to 1,270 elderly patients (≥ 60 years) were gathered from a database. These prescriptions had been written by geriatricians at a tertiary-level university hospital in São Paulo, Brazil, between February and May 2008. The prescriptions were divided according to sex and age group (60-69, 70-79 and ≥ 80). The Beers criteria were used to evaluate PIMs.RESULTSMost of the sample comprised women (77%) and the mean age was 80.1 years. The mean prevalence of PIM prescriptions was 26.9%. Female sex and number of medications prescribed were associated with prescription of PIMs. The chance of having a PIM prescription was lower among patients ≥ 70 years.CONCLUSIONThe greater prevalence of PIMs was correlated with female sex. The chance of having a PIM prescription was lower among patients ≥ 70 years and became greater with increasing numbers of medications prescribed (≥ 7).http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802013000100019&lng=en&tlng=enGeriatricsPharmacoepidemiologyPrescriptionsAmbulatory careAged
spellingShingle Christine Grützmann Faustino
Maria Cristina Guerra Passarelli
Wilson Jacob-Filho
Potentially inappropriate medications among elderly Brazilian outpatients
São Paulo Medical Journal
Geriatrics
Pharmacoepidemiology
Prescriptions
Ambulatory care
Aged
title Potentially inappropriate medications among elderly Brazilian outpatients
title_full Potentially inappropriate medications among elderly Brazilian outpatients
title_fullStr Potentially inappropriate medications among elderly Brazilian outpatients
title_full_unstemmed Potentially inappropriate medications among elderly Brazilian outpatients
title_short Potentially inappropriate medications among elderly Brazilian outpatients
title_sort potentially inappropriate medications among elderly brazilian outpatients
topic Geriatrics
Pharmacoepidemiology
Prescriptions
Ambulatory care
Aged
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802013000100019&lng=en&tlng=en
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