Intratumoral OH2, an oncolytic herpes simplex virus 2, in patients with advanced solid tumors: a multicenter, phase I/II clinical trial

Intratumoral OH2, an oncolytic herpes simplex virus 2, in patients with advanced solid tumors: a multicenter, phase I/II clinical trial

Background OH2 is a genetically engineered oncolytic herpes simplex virus type 2 designed to selectively amplify in tumor cells and express granulocyte-macrophage colony-stimulating factor to enhance antitumor immune responses. We investigated the safety, tolerability and antitumor activity of OH2 a...

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Bibliographic Details
Main Authors:	Jialin Tang, Sheng Hu, Suxia Luo, Zhiguo Luo, Fuxiang Zhou, Shiyun Tan, Jieer Ying, Chengyun Geng, Xiangyong Gu, Binlei Liu
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2021-04-01
Series:	Journal for ImmunoTherapy of Cancer
Online Access:	https://jitc.bmj.com/content/9/4/e002224.full

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