Supratherapeutic international normalized ratio: an indicator of chronic malnutrition due to severely debilitating gastrointestinal disease

This case highlights the fact that Supratherapeutic INRs direct the attention of the treating physicians’ team to the underlying severely debilitating gastrointestinal diseases. Prolonged fasting or starvation reduces vitamin K levels. Such patients are more sensitive to treatment with Vitamin K ant...

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Main Authors: Sarwan Kumar, Deepak Gupta, Shiva S. Rau
Format: Article
Language:English
Published: MDPI AG 2011-04-01
Series:Clinics and Practice
Subjects:
Online Access:https://www.clinicsandpractice.org/index.php/cp/article/view/22
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author Sarwan Kumar
Deepak Gupta
Shiva S. Rau
author_facet Sarwan Kumar
Deepak Gupta
Shiva S. Rau
author_sort Sarwan Kumar
collection DOAJ
description This case highlights the fact that Supratherapeutic INRs direct the attention of the treating physicians’ team to the underlying severely debilitating gastrointestinal diseases. Prolonged fasting or starvation reduces vitamin K levels. Such patients are more sensitive to treatment with Vitamin K antagonist-based anticoagulants. Hence, the Supratherapeutic INR can be an objective indicator of chronic loss of appetite with poor nutritional status of the patient and therefore acts as a warning sign for diagnosis of severe debilitating primary gastrointestinal disease.
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spelling doaj.art-c2746c4f60d0416686e077d4767363132022-12-22T04:21:08ZengMDPI AGClinics and Practice2039-72752039-72832011-04-011210.4081/cp.2011.e2121Supratherapeutic international normalized ratio: an indicator of chronic malnutrition due to severely debilitating gastrointestinal diseaseSarwan Kumar0Deepak Gupta1Shiva S. Rau2Department of Internal Medicine, Wayne State University/Detroit Medical CenterDepartment of Anesthesiology, Wayne State University/Detroit Medical CenterDepartment of Internal Medicine, Wayne State University/Detroit Medical CenterThis case highlights the fact that Supratherapeutic INRs direct the attention of the treating physicians’ team to the underlying severely debilitating gastrointestinal diseases. Prolonged fasting or starvation reduces vitamin K levels. Such patients are more sensitive to treatment with Vitamin K antagonist-based anticoagulants. Hence, the Supratherapeutic INR can be an objective indicator of chronic loss of appetite with poor nutritional status of the patient and therefore acts as a warning sign for diagnosis of severe debilitating primary gastrointestinal disease.https://www.clinicsandpractice.org/index.php/cp/article/view/22Supratherapeutic INRs
spellingShingle Sarwan Kumar
Deepak Gupta
Shiva S. Rau
Supratherapeutic international normalized ratio: an indicator of chronic malnutrition due to severely debilitating gastrointestinal disease
Clinics and Practice
Supratherapeutic INRs
title Supratherapeutic international normalized ratio: an indicator of chronic malnutrition due to severely debilitating gastrointestinal disease
title_full Supratherapeutic international normalized ratio: an indicator of chronic malnutrition due to severely debilitating gastrointestinal disease
title_fullStr Supratherapeutic international normalized ratio: an indicator of chronic malnutrition due to severely debilitating gastrointestinal disease
title_full_unstemmed Supratherapeutic international normalized ratio: an indicator of chronic malnutrition due to severely debilitating gastrointestinal disease
title_short Supratherapeutic international normalized ratio: an indicator of chronic malnutrition due to severely debilitating gastrointestinal disease
title_sort supratherapeutic international normalized ratio an indicator of chronic malnutrition due to severely debilitating gastrointestinal disease
topic Supratherapeutic INRs
url https://www.clinicsandpractice.org/index.php/cp/article/view/22
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