Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report

Toxoplasmosis is a rare but potentially severe complication after allogeneic hematopoietic cell transplantation. Toxoplasma gondii-associated cardiac involvement can cause myocarditis, pericarditis, arrhythmias, and congestive heart failure. Most cases with cardiac toxoplasmosis following BMT have b...

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Bibliographic Details
Main Authors: Padmastuti Akella, Isha Bhatt, Mustapha Serhan, Dilip D. Giri, Stephen M. Pastores
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:IDCases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214250921001736
Description
Summary:Toxoplasmosis is a rare but potentially severe complication after allogeneic hematopoietic cell transplantation. Toxoplasma gondii-associated cardiac involvement can cause myocarditis, pericarditis, arrhythmias, and congestive heart failure. Most cases with cardiac toxoplasmosis following BMT have been fatal and diagnosed at autopsy. We present an unfortunate case of sudden onset congestive heart failure symptoms and delayed post-transplant Toxoplasma PCR testing that ultimately led to the diagnosis of cardiac toxoplasmosis on autopsy in our patient.
ISSN:2214-2509