Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report

Toxoplasmosis is a rare but potentially severe complication after allogeneic hematopoietic cell transplantation. Toxoplasma gondii-associated cardiac involvement can cause myocarditis, pericarditis, arrhythmias, and congestive heart failure. Most cases with cardiac toxoplasmosis following BMT have b...

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Main Authors: Padmastuti Akella, Isha Bhatt, Mustapha Serhan, Dilip D. Giri, Stephen M. Pastores
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:IDCases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214250921001736
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author Padmastuti Akella
Isha Bhatt
Mustapha Serhan
Dilip D. Giri
Stephen M. Pastores
author_facet Padmastuti Akella
Isha Bhatt
Mustapha Serhan
Dilip D. Giri
Stephen M. Pastores
author_sort Padmastuti Akella
collection DOAJ
description Toxoplasmosis is a rare but potentially severe complication after allogeneic hematopoietic cell transplantation. Toxoplasma gondii-associated cardiac involvement can cause myocarditis, pericarditis, arrhythmias, and congestive heart failure. Most cases with cardiac toxoplasmosis following BMT have been fatal and diagnosed at autopsy. We present an unfortunate case of sudden onset congestive heart failure symptoms and delayed post-transplant Toxoplasma PCR testing that ultimately led to the diagnosis of cardiac toxoplasmosis on autopsy in our patient.
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spelling doaj.art-c27490b7616845829db817493206bb1b2022-12-21T22:30:51ZengElsevierIDCases2214-25092021-01-0125e01217Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case reportPadmastuti Akella0Isha Bhatt1Mustapha Serhan2Dilip D. Giri3Stephen M. Pastores4Corresponding author at: Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, United States.; Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, United StatesDepartment of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, United StatesDepartment of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, United StatesDepartment of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, United StatesDepartment of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, United StatesToxoplasmosis is a rare but potentially severe complication after allogeneic hematopoietic cell transplantation. Toxoplasma gondii-associated cardiac involvement can cause myocarditis, pericarditis, arrhythmias, and congestive heart failure. Most cases with cardiac toxoplasmosis following BMT have been fatal and diagnosed at autopsy. We present an unfortunate case of sudden onset congestive heart failure symptoms and delayed post-transplant Toxoplasma PCR testing that ultimately led to the diagnosis of cardiac toxoplasmosis on autopsy in our patient.http://www.sciencedirect.com/science/article/pii/S2214250921001736ToxoplasmosisCardiacHematopoietic stem cell transplantParasitic infectionAutopsyPCR
spellingShingle Padmastuti Akella
Isha Bhatt
Mustapha Serhan
Dilip D. Giri
Stephen M. Pastores
Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report
IDCases
Toxoplasmosis
Cardiac
Hematopoietic stem cell transplant
Parasitic infection
Autopsy
PCR
title Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report
title_full Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report
title_fullStr Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report
title_full_unstemmed Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report
title_short Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report
title_sort toxic toxo in the heart cardiac toxoplasmosis following a hematopoietic stem cell transplant a case report
topic Toxoplasmosis
Cardiac
Hematopoietic stem cell transplant
Parasitic infection
Autopsy
PCR
url http://www.sciencedirect.com/science/article/pii/S2214250921001736
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AT dilipdgiri toxictoxointheheartcardiactoxoplasmosisfollowingahematopoieticstemcelltransplantacasereport
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