Reduction in viability oh human cervix carcinoma HeLa cells by p21 gene transferred with block polymeric dimethylaminoethyl methacrylate-based carrier

Reduction in viability oh human cervix carcinoma HeLa cells by p21 gene transferred with block polymeric dimethylaminoethyl methacrylate-based carrier

Background. Various cationic polymers have been proposed for use as carriers of genetic materials in biotechnology and biomedicine. The poly(2-dimethylamino)ethyl-methacrylate (poly(DMAEMA)) demonstrated high transfection efficiency and low cytotoxicity when used as a gene delivery system. The aim o...

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Bibliographic Details
Main Authors:	N. S. Finiuk, N. E. Mitina, O. Yu. Klyuchivska, I. Y. Kril, A. S. Zaichenko, R. S. Stoika
Format:	Article
Language:	English
Published:	Львівський національний університет імені Івана Франка 2022-07-01
Series:	Біологічні студії
Subjects:	poly(2-dimethylamino)ethyl-methacrylate polymeric carrier gene transfer p21 cytotoxic action cell cycle dna damage
Online Access:	http://publications.lnu.edu.ua/journals/index.php/biology/article/view/1427

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