Treatment Patterns for and Characteristics of Headache in Children and Adolescents Aged 6–17 Years in Japan: A Retrospective Cross-Sectional and Longitudinal Analysis of Health Insurance Claims Data
Objective: To investigate the prescription patterns for patients aged 6–17 years with headaches in the REZULT database. Methods: We cross-sectionally investigated (Study 1) the pattern of prescription and the proportion of triptan overprescription (≥30 tablets/90 d of triptans) among patients diagno...
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MDPI AG
2024-01-01
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| Online Access: | https://www.mdpi.com/2075-1729/14/1/96 |
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| author | Masahito Katsuki Yasuhiko Matsumori Taisuke Ichihara Yuya Yamada Shin Kawamura Kenta Kashiwagi Akihito Koh Tetsuya Goto Kazuma Kaneko Naomichi Wada Fuminori Yamagishi |
| author_facet | Masahito Katsuki Yasuhiko Matsumori Taisuke Ichihara Yuya Yamada Shin Kawamura Kenta Kashiwagi Akihito Koh Tetsuya Goto Kazuma Kaneko Naomichi Wada Fuminori Yamagishi |
| author_sort | Masahito Katsuki |
| collection | DOAJ |
| description | Objective: To investigate the prescription patterns for patients aged 6–17 years with headaches in the REZULT database. Methods: We cross-sectionally investigated (Study 1) the pattern of prescription and the proportion of triptan overprescription (≥30 tablets/90 d of triptans) among patients diagnosed with headaches in 2020. Next, we longitudinally studied patients (Study 2) for more than two years from the initial headache diagnosis (July 2010 to April 2022). The number of prescribed tablets was counted every 90 days. Results: In Study 1, headache diagnoses were assigned to 62,568 of 543,628 (11.51%) patients, and 1524 of 62,568 (2.44%) patients received acute medication. Single nonsteroidal anti-inflammatory drugs and triptans were prescribed to 620/624 (99.36%) and 5/624 (0.80%) of patients aged 6–11 years, respectively, and 827/900 (91.89%) and 91/900 (10.11%) of patients aged 12–17 years, respectively. Triptan overprescription was observed in 11/96 (11.46%) patients, and 5/11 (45.45%) of those patients received prophylactic medication. In Study 2, 80,756/845,470 (9.55%) patients aged 6–17 years were diagnosed with headaches that persisted for at least two years. Over two years, 44/80,756 (0.05%) patients were overprescribed triptans, and 3408/80,756 (4.22%) patients were prescribed prophylaxis on at least one occasion. Conclusions: Based on real-world data, the appropriate use of prophylactic treatment is still problematic. Overprescription of triptans was observed, although the number of patients was small. |
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| language | English |
| last_indexed | 2024-03-08T10:44:40Z |
| publishDate | 2024-01-01 |
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| series | Life |
| spelling | doaj.art-c27e47c2cc5841959edeb6c468cbaebe2024-01-26T17:20:55ZengMDPI AGLife2075-17292024-01-011419610.3390/life14010096Treatment Patterns for and Characteristics of Headache in Children and Adolescents Aged 6–17 Years in Japan: A Retrospective Cross-Sectional and Longitudinal Analysis of Health Insurance Claims DataMasahito Katsuki0Yasuhiko Matsumori1Taisuke Ichihara2Yuya Yamada3Shin Kawamura4Kenta Kashiwagi5Akihito Koh6Tetsuya Goto7Kazuma Kaneko8Naomichi Wada9Fuminori Yamagishi10Department of Neurosurgery, Suwa Red Cross Hospital, Suwa 392-0027, JapanSendai Headache and Neurology Clinic, Sendai 982-0014, JapanJapan System Techniques Co., Ltd. (JAST), Minato-ku 108-8288, JapanJapan System Techniques Co., Ltd. (JAST), Minato-ku 108-8288, JapanDepartment of Neurosurgery, Itoigawa General Hospital, Itoigawa 941-0006, JapanDepartment of Neurology, Itoigawa General Hospital, Itoigawa 941-0006, JapanDepartment of Neurosurgery, Itoigawa General Hospital, Itoigawa 941-0006, JapanDepartment of Neurosurgery, Suwa Red Cross Hospital, Suwa 392-0027, JapanHeadache Outpatient, Suwa Red Cross Hospital, Suwa 392-0027, JapanDepartment of Neurosurgery, Suwa Red Cross Hospital, Suwa 392-0027, JapanDepartment of Surgery, Itoigawa General Hospital, Itoigawa 941-0006, JapanObjective: To investigate the prescription patterns for patients aged 6–17 years with headaches in the REZULT database. Methods: We cross-sectionally investigated (Study 1) the pattern of prescription and the proportion of triptan overprescription (≥30 tablets/90 d of triptans) among patients diagnosed with headaches in 2020. Next, we longitudinally studied patients (Study 2) for more than two years from the initial headache diagnosis (July 2010 to April 2022). The number of prescribed tablets was counted every 90 days. Results: In Study 1, headache diagnoses were assigned to 62,568 of 543,628 (11.51%) patients, and 1524 of 62,568 (2.44%) patients received acute medication. Single nonsteroidal anti-inflammatory drugs and triptans were prescribed to 620/624 (99.36%) and 5/624 (0.80%) of patients aged 6–11 years, respectively, and 827/900 (91.89%) and 91/900 (10.11%) of patients aged 12–17 years, respectively. Triptan overprescription was observed in 11/96 (11.46%) patients, and 5/11 (45.45%) of those patients received prophylactic medication. In Study 2, 80,756/845,470 (9.55%) patients aged 6–17 years were diagnosed with headaches that persisted for at least two years. Over two years, 44/80,756 (0.05%) patients were overprescribed triptans, and 3408/80,756 (4.22%) patients were prescribed prophylaxis on at least one occasion. Conclusions: Based on real-world data, the appropriate use of prophylactic treatment is still problematic. Overprescription of triptans was observed, although the number of patients was small.https://www.mdpi.com/2075-1729/14/1/96migrainepediatricacute mediationstriptansmedication overuse headache |
| spellingShingle | Masahito Katsuki Yasuhiko Matsumori Taisuke Ichihara Yuya Yamada Shin Kawamura Kenta Kashiwagi Akihito Koh Tetsuya Goto Kazuma Kaneko Naomichi Wada Fuminori Yamagishi Treatment Patterns for and Characteristics of Headache in Children and Adolescents Aged 6–17 Years in Japan: A Retrospective Cross-Sectional and Longitudinal Analysis of Health Insurance Claims Data Life migraine pediatric acute mediations triptans medication overuse headache |
| title | Treatment Patterns for and Characteristics of Headache in Children and Adolescents Aged 6–17 Years in Japan: A Retrospective Cross-Sectional and Longitudinal Analysis of Health Insurance Claims Data |
| title_full | Treatment Patterns for and Characteristics of Headache in Children and Adolescents Aged 6–17 Years in Japan: A Retrospective Cross-Sectional and Longitudinal Analysis of Health Insurance Claims Data |
| title_fullStr | Treatment Patterns for and Characteristics of Headache in Children and Adolescents Aged 6–17 Years in Japan: A Retrospective Cross-Sectional and Longitudinal Analysis of Health Insurance Claims Data |
| title_full_unstemmed | Treatment Patterns for and Characteristics of Headache in Children and Adolescents Aged 6–17 Years in Japan: A Retrospective Cross-Sectional and Longitudinal Analysis of Health Insurance Claims Data |
| title_short | Treatment Patterns for and Characteristics of Headache in Children and Adolescents Aged 6–17 Years in Japan: A Retrospective Cross-Sectional and Longitudinal Analysis of Health Insurance Claims Data |
| title_sort | treatment patterns for and characteristics of headache in children and adolescents aged 6 17 years in japan a retrospective cross sectional and longitudinal analysis of health insurance claims data |
| topic | migraine pediatric acute mediations triptans medication overuse headache |
| url | https://www.mdpi.com/2075-1729/14/1/96 |
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