The evolution of personalized medicine: literature review

"Personalized" medicine is based on the belief that each person has unique molecular, physiological, environmental and behavioral characteristics and in case of disease development each patient should be treated taking into account these unique characteristics. This belief was to somehow c...

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Main Authors: I. S. Dolgopolov, M. Yu. Rykov
Format: Article
Language:Russian
Published: QUASAR, LLC 2022-09-01
Series:Issledovaniâ i Praktika v Medicine
Subjects:
Online Access:https://www.rpmj.ru/rpmj/article/view/774
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author I. S. Dolgopolov
M. Yu. Rykov
author_facet I. S. Dolgopolov
M. Yu. Rykov
author_sort I. S. Dolgopolov
collection DOAJ
description "Personalized" medicine is based on the belief that each person has unique molecular, physiological, environmental and behavioral characteristics and in case of disease development each patient should be treated taking into account these unique characteristics. This belief was to somehow confirmed by the use of the latest technologies, such as DNA sequencing, proteomics, imaging protocols and the use of wireless devices for health monitoring, which revealed inter-individual differences in gene expression and penetrance levels. A search was conducted for literary sources (scientific articles), including those published in peer-reviewed journals indexed in Pubmed, WOS, Scopus and RSCI from 2010 to 2021. The review includes 49 articles on personalized medicine. The technologies that make personalized medicine possible, new experience, methods of testing and prospects for the use of individually selected medicinal preparations, as well as potential approaches to the treatment of people with fertility problems and infertility are considered. It can be assumed that the individualization of medical practice will develop, especially in the case of rare genetic diseases. Moreover, an individual approach to the patient is more effective and rentable.
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spelling doaj.art-c28830cf1b004e2695bf5509652030502023-03-13T09:35:02ZrusQUASAR, LLCIssledovaniâ i Praktika v Medicine2410-18932022-09-019311712810.17709/2410-1893-2022-9-3-9461The evolution of personalized medicine: literature reviewI. S. Dolgopolov0M. Yu. Rykov1Тверской ГМУ Минздрава РоссииТверской ГМУ Минздрава России; Национальный НИИ общественного здоровья им. Н. А. Семашко"Personalized" medicine is based on the belief that each person has unique molecular, physiological, environmental and behavioral characteristics and in case of disease development each patient should be treated taking into account these unique characteristics. This belief was to somehow confirmed by the use of the latest technologies, such as DNA sequencing, proteomics, imaging protocols and the use of wireless devices for health monitoring, which revealed inter-individual differences in gene expression and penetrance levels. A search was conducted for literary sources (scientific articles), including those published in peer-reviewed journals indexed in Pubmed, WOS, Scopus and RSCI from 2010 to 2021. The review includes 49 articles on personalized medicine. The technologies that make personalized medicine possible, new experience, methods of testing and prospects for the use of individually selected medicinal preparations, as well as potential approaches to the treatment of people with fertility problems and infertility are considered. It can be assumed that the individualization of medical practice will develop, especially in the case of rare genetic diseases. Moreover, an individual approach to the patient is more effective and rentable.https://www.rpmj.ru/rpmj/article/view/774персонифицированная медицинаобзорбиомаркерыпротеомикагеномика
spellingShingle I. S. Dolgopolov
M. Yu. Rykov
The evolution of personalized medicine: literature review
Issledovaniâ i Praktika v Medicine
персонифицированная медицина
обзор
биомаркеры
протеомика
геномика
title The evolution of personalized medicine: literature review
title_full The evolution of personalized medicine: literature review
title_fullStr The evolution of personalized medicine: literature review
title_full_unstemmed The evolution of personalized medicine: literature review
title_short The evolution of personalized medicine: literature review
title_sort evolution of personalized medicine literature review
topic персонифицированная медицина
обзор
биомаркеры
протеомика
геномика
url https://www.rpmj.ru/rpmj/article/view/774
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