| Summary: | INTRODUCTION[|]Coronavirus disease 2019 (COVID-19)-related infections emerging from China that spread worldwide show a wide range of clinical courses from asymptomatic presentation to respiratory failure and even death. Similar to non-COVID-19 infections, obesity, age, and comorbidities can also affect the clinical course of the disease. This study aimed to investigate the effect of obesity on the clinical course and mortality of patients hospitalized with COVID-19 pneumonia.[¤]METHODS[|]Between March 11 and April 30, 2020, patients hospitalized with COVID-19 pneumonia were retrospectively analyzed. Patients were classified as having severe and mild disease based on oxygen, non-invasive mechanical ventilation (NIMV), and invasive (IMV) mechanical ventilation requirements. Two groups were evaluated based on body mass index (BMI) of ≥25 and ≥30 kg/m2.[¤]RESULTS[|]Of the 125 patients, 82 (65.6%) were men, and their mean age was 51.77+-4.99 years. Their mean BMI was 27.76+-4.76 kg/m2. The difference of the mean BMI between the patients with severe and mild disease was statistically significant (28.8+-5.36 and 26.9+-4.10, respectively) (p=0.028). BMI of ≥25 and ≥30 kg/m2 were noted in 43.4% and 20.8% of patients with severe and mild disease, respectively, which was statistically significant (p=0.007). Moreover, 70.6% of 17 patients older than 65 years with BMI of ≥25 kg/m2 had a severe clinical course (p=0.021). Among patients requiring NIMV, 59.1% and 31.8% had a BMI of ≥25 and 30 kg/m2, respectively. Among patients requiring IMV, 66.7% and 37.5% had a BMI of ≥25 and 30 kg/m2, respectively. No statistically significant difference was found between BMI and NIMV and IMV need. Death occurred in 14.8% of the patients. No statistically significant difference was found between the BMI of those who died and survived (p=0.768).[¤]DISCUSSION AND CONCLUSION[|]Bu kohort çalışması, aşırı kilo ve obezitenin hastalık şiddetini değerlendirmede ve tahminde önemli bir faktör olduğunu ve özellikle VKİ ≥30 kg/m2 olan hastaların takiplerinde dikkatli olunması gerektiğini göstermiştir.[¤]
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