Is Body Mass Index A Risk Factor in the Clinical Course of Patients with Coronavirus Disease 2019 Pneumonia?
INTRODUCTION[|]Coronavirus disease 2019 (COVID-19)-related infections emerging from China that spread worldwide show a wide range of clinical courses from asymptomatic presentation to respiratory failure and even death. Similar to non-COVID-19 infections, obesity, age, and comorbidities can also aff...
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| Format: | Article |
| Language: | English |
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KARE Publishing
2021-01-01
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| Series: | Southern Clinics of Istanbul Eurasia |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=scie&un=SCIE-29974 |
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| author | Demet Turan Elif Tanrıverdi Mustafa Çörtük Binnaz Zeynep Yıldırım Efsun Gonca Uğur Chousein Halit Çınarka Mehmet Akif Özgul Erdoğan Çetinkaya |
| author_facet | Demet Turan Elif Tanrıverdi Mustafa Çörtük Binnaz Zeynep Yıldırım Efsun Gonca Uğur Chousein Halit Çınarka Mehmet Akif Özgul Erdoğan Çetinkaya |
| author_sort | Demet Turan |
| collection | DOAJ |
| description | INTRODUCTION[|]Coronavirus disease 2019 (COVID-19)-related infections emerging from China that spread worldwide show a wide range of clinical courses from asymptomatic presentation to respiratory failure and even death. Similar to non-COVID-19 infections, obesity, age, and comorbidities can also affect the clinical course of the disease. This study aimed to investigate the effect of obesity on the clinical course and mortality of patients hospitalized with COVID-19 pneumonia.[¤]METHODS[|]Between March 11 and April 30, 2020, patients hospitalized with COVID-19 pneumonia were retrospectively analyzed. Patients were classified as having severe and mild disease based on oxygen, non-invasive mechanical ventilation (NIMV), and invasive (IMV) mechanical ventilation requirements. Two groups were evaluated based on body mass index (BMI) of ≥25 and ≥30 kg/m2.[¤]RESULTS[|]Of the 125 patients, 82 (65.6%) were men, and their mean age was 51.77+-4.99 years. Their mean BMI was 27.76+-4.76 kg/m2. The difference of the mean BMI between the patients with severe and mild disease was statistically significant (28.8+-5.36 and 26.9+-4.10, respectively) (p=0.028). BMI of ≥25 and ≥30 kg/m2 were noted in 43.4% and 20.8% of patients with severe and mild disease, respectively, which was statistically significant (p=0.007). Moreover, 70.6% of 17 patients older than 65 years with BMI of ≥25 kg/m2 had a severe clinical course (p=0.021). Among patients requiring NIMV, 59.1% and 31.8% had a BMI of ≥25 and 30 kg/m2, respectively. Among patients requiring IMV, 66.7% and 37.5% had a BMI of ≥25 and 30 kg/m2, respectively. No statistically significant difference was found between BMI and NIMV and IMV need. Death occurred in 14.8% of the patients. No statistically significant difference was found between the BMI of those who died and survived (p=0.768).[¤]DISCUSSION AND CONCLUSION[|]Bu kohort çalışması, aşırı kilo ve obezitenin hastalık şiddetini değerlendirmede ve tahminde önemli bir faktör olduğunu ve özellikle VKİ ≥30 kg/m2 olan hastaların takiplerinde dikkatli olunması gerektiğini göstermiştir.[¤] |
| first_indexed | 2024-04-10T10:57:48Z |
| format | Article |
| id | doaj.art-c28b616cf98c4effa78e1f1132023f31 |
| institution | Directory Open Access Journal |
| issn | 2587-0998 |
| language | English |
| last_indexed | 2024-04-10T10:57:48Z |
| publishDate | 2021-01-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Southern Clinics of Istanbul Eurasia |
| spelling | doaj.art-c28b616cf98c4effa78e1f1132023f312023-02-15T16:19:49ZengKARE PublishingSouthern Clinics of Istanbul Eurasia2587-09982021-01-0131432432810.14744/scie.2020.29974SCIE-29974Is Body Mass Index A Risk Factor in the Clinical Course of Patients with Coronavirus Disease 2019 Pneumonia?Demet Turan0Elif Tanrıverdi1Mustafa Çörtük2Binnaz Zeynep Yıldırım3Efsun Gonca Uğur Chousein4Halit Çınarka5Mehmet Akif Özgul6Erdoğan Çetinkaya7Department of Pulmonology, University of Health Sciences, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, TurkeyDepartment of Pulmonology, University of Health Sciences, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, TurkeyDepartment of Pulmonology, University of Health Sciences, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, TurkeyDepartment of Pulmonology, University of Health Sciences, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, TurkeyDepartment of Pulmonology, University of Health Sciences, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, TurkeyDepartment of Pulmonology, University of Health Sciences, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, TurkeyDepartment of Pulmonology, University of Health Sciences, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, TurkeyDepartment of Pulmonology, University of Health Sciences, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, TurkeyINTRODUCTION[|]Coronavirus disease 2019 (COVID-19)-related infections emerging from China that spread worldwide show a wide range of clinical courses from asymptomatic presentation to respiratory failure and even death. Similar to non-COVID-19 infections, obesity, age, and comorbidities can also affect the clinical course of the disease. This study aimed to investigate the effect of obesity on the clinical course and mortality of patients hospitalized with COVID-19 pneumonia.[¤]METHODS[|]Between March 11 and April 30, 2020, patients hospitalized with COVID-19 pneumonia were retrospectively analyzed. Patients were classified as having severe and mild disease based on oxygen, non-invasive mechanical ventilation (NIMV), and invasive (IMV) mechanical ventilation requirements. Two groups were evaluated based on body mass index (BMI) of ≥25 and ≥30 kg/m2.[¤]RESULTS[|]Of the 125 patients, 82 (65.6%) were men, and their mean age was 51.77+-4.99 years. Their mean BMI was 27.76+-4.76 kg/m2. The difference of the mean BMI between the patients with severe and mild disease was statistically significant (28.8+-5.36 and 26.9+-4.10, respectively) (p=0.028). BMI of ≥25 and ≥30 kg/m2 were noted in 43.4% and 20.8% of patients with severe and mild disease, respectively, which was statistically significant (p=0.007). Moreover, 70.6% of 17 patients older than 65 years with BMI of ≥25 kg/m2 had a severe clinical course (p=0.021). Among patients requiring NIMV, 59.1% and 31.8% had a BMI of ≥25 and 30 kg/m2, respectively. Among patients requiring IMV, 66.7% and 37.5% had a BMI of ≥25 and 30 kg/m2, respectively. No statistically significant difference was found between BMI and NIMV and IMV need. Death occurred in 14.8% of the patients. No statistically significant difference was found between the BMI of those who died and survived (p=0.768).[¤]DISCUSSION AND CONCLUSION[|]Bu kohort çalışması, aşırı kilo ve obezitenin hastalık şiddetini değerlendirmede ve tahminde önemli bir faktör olduğunu ve özellikle VKİ ≥30 kg/m2 olan hastaların takiplerinde dikkatli olunması gerektiğini göstermiştir.[¤]https://jag.journalagent.com/z4/download_fulltext.asp?pdir=scie&un=SCIE-29974body mass indexcovid-19; pneumonia; severe disease. |
| spellingShingle | Demet Turan Elif Tanrıverdi Mustafa Çörtük Binnaz Zeynep Yıldırım Efsun Gonca Uğur Chousein Halit Çınarka Mehmet Akif Özgul Erdoğan Çetinkaya Is Body Mass Index A Risk Factor in the Clinical Course of Patients with Coronavirus Disease 2019 Pneumonia? Southern Clinics of Istanbul Eurasia body mass index covid-19; pneumonia; severe disease. |
| title | Is Body Mass Index A Risk Factor in the Clinical Course of Patients with Coronavirus Disease 2019 Pneumonia? |
| title_full | Is Body Mass Index A Risk Factor in the Clinical Course of Patients with Coronavirus Disease 2019 Pneumonia? |
| title_fullStr | Is Body Mass Index A Risk Factor in the Clinical Course of Patients with Coronavirus Disease 2019 Pneumonia? |
| title_full_unstemmed | Is Body Mass Index A Risk Factor in the Clinical Course of Patients with Coronavirus Disease 2019 Pneumonia? |
| title_short | Is Body Mass Index A Risk Factor in the Clinical Course of Patients with Coronavirus Disease 2019 Pneumonia? |
| title_sort | is body mass index a risk factor in the clinical course of patients with coronavirus disease 2019 pneumonia |
| topic | body mass index covid-19; pneumonia; severe disease. |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=scie&un=SCIE-29974 |
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