Cancer Chemoprevention Using Nanotechnology-Based Approaches

Cancer research in pursuit of better diagnostic and treatment modalities has seen great advances in recent years. However, the incidence rate of cancer is still very high. Almost 40% of women and men are diagnosed with cancer during their lifetime. Such high incidence has not only resulted in high m...

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Main Authors: Preshita Desai, Naga Jyothi Thumma, Pushkaraj Rajendra Wagh, Shuyu Zhan, David Ann, Jeffrey Wang, Sunil Prabhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00323/full
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author Preshita Desai
Naga Jyothi Thumma
Pushkaraj Rajendra Wagh
Shuyu Zhan
Shuyu Zhan
David Ann
Jeffrey Wang
Sunil Prabhu
author_facet Preshita Desai
Naga Jyothi Thumma
Pushkaraj Rajendra Wagh
Shuyu Zhan
Shuyu Zhan
David Ann
Jeffrey Wang
Sunil Prabhu
author_sort Preshita Desai
collection DOAJ
description Cancer research in pursuit of better diagnostic and treatment modalities has seen great advances in recent years. However, the incidence rate of cancer is still very high. Almost 40% of women and men are diagnosed with cancer during their lifetime. Such high incidence has not only resulted in high mortality but also severely compromised patient lifestyles, and added a great socioeconomic burden. In view of this, chemoprevention has gained wide attention as a method to reduce cancer incidence and its relapse after treatment. Among various stems of chemoprevention research, nanotechnology-based chemoprevention approaches have established their potential to offer better efficacy and safety. This review summarizes recent advances in nanotechnology-based chemoprevention strategies for various cancers with emphasis on lung and bronchial cancer, colorectal, pancreatic, and breast cancer and highlights the unmet needs in this developing field towards successful clinical translation.
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spelling doaj.art-c28bda2505374579acfecd3abdeff1a82022-12-22T02:21:55ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122020-04-011110.3389/fphar.2020.00323521769Cancer Chemoprevention Using Nanotechnology-Based ApproachesPreshita Desai0Naga Jyothi Thumma1Pushkaraj Rajendra Wagh2Shuyu Zhan3Shuyu Zhan4David Ann5Jeffrey Wang6Sunil Prabhu7Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA, United StatesDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA, United StatesDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA, United StatesDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA, United StatesDepartment of Pharmaceutics, College of Medicine, Jiaxing University, Jiaxing, ChinaDepartment of Diabetes and Metabolic Diseases Research, Beckman Research Institute, City of Hope, Duarte, CA, United StatesDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA, United StatesDepartment of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA, United StatesCancer research in pursuit of better diagnostic and treatment modalities has seen great advances in recent years. However, the incidence rate of cancer is still very high. Almost 40% of women and men are diagnosed with cancer during their lifetime. Such high incidence has not only resulted in high mortality but also severely compromised patient lifestyles, and added a great socioeconomic burden. In view of this, chemoprevention has gained wide attention as a method to reduce cancer incidence and its relapse after treatment. Among various stems of chemoprevention research, nanotechnology-based chemoprevention approaches have established their potential to offer better efficacy and safety. This review summarizes recent advances in nanotechnology-based chemoprevention strategies for various cancers with emphasis on lung and bronchial cancer, colorectal, pancreatic, and breast cancer and highlights the unmet needs in this developing field towards successful clinical translation.https://www.frontiersin.org/article/10.3389/fphar.2020.00323/fullchemopreventionnanotechnologytargeted deliveryefficacyrelapse
spellingShingle Preshita Desai
Naga Jyothi Thumma
Pushkaraj Rajendra Wagh
Shuyu Zhan
Shuyu Zhan
David Ann
Jeffrey Wang
Sunil Prabhu
Cancer Chemoprevention Using Nanotechnology-Based Approaches
Frontiers in Pharmacology
chemoprevention
nanotechnology
targeted delivery
efficacy
relapse
title Cancer Chemoprevention Using Nanotechnology-Based Approaches
title_full Cancer Chemoprevention Using Nanotechnology-Based Approaches
title_fullStr Cancer Chemoprevention Using Nanotechnology-Based Approaches
title_full_unstemmed Cancer Chemoprevention Using Nanotechnology-Based Approaches
title_short Cancer Chemoprevention Using Nanotechnology-Based Approaches
title_sort cancer chemoprevention using nanotechnology based approaches
topic chemoprevention
nanotechnology
targeted delivery
efficacy
relapse
url https://www.frontiersin.org/article/10.3389/fphar.2020.00323/full
work_keys_str_mv AT preshitadesai cancerchemopreventionusingnanotechnologybasedapproaches
AT nagajyothithumma cancerchemopreventionusingnanotechnologybasedapproaches
AT pushkarajrajendrawagh cancerchemopreventionusingnanotechnologybasedapproaches
AT shuyuzhan cancerchemopreventionusingnanotechnologybasedapproaches
AT shuyuzhan cancerchemopreventionusingnanotechnologybasedapproaches
AT davidann cancerchemopreventionusingnanotechnologybasedapproaches
AT jeffreywang cancerchemopreventionusingnanotechnologybasedapproaches
AT sunilprabhu cancerchemopreventionusingnanotechnologybasedapproaches