The possible role of maternal and placental vitamin D receptor polymorphisms and haplotypes in pathogenesis of preeclampsia

The possible role of maternal and placental vitamin D receptor polymorphisms and haplotypes in pathogenesis of preeclampsia

Purpose: Vitamin D deficiency may be a main causative agent in the pathogenesis of preeclampsia (PE). The actions of the active form of vitamin D are mediated via the vitamin D receptor (VDR), which is expressed in numerous organs including placenta. Therefore, we evaluated the potential relationshi...

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Main Authors: Farzaneh Farajian-Mashhadi, Fatemeh Eskandari, Mahnaz Rezaei, Farzaneh Eskandari, Darya Najafi, Batool Teimoori, Maryam Moradi-Sharbabak, Saeedeh Salimi
Format: Article
Language:English
Published: Taylor & Francis Group 2020-02-01
Series:Clinical and Experimental Hypertension
Subjects:
placenta
polymorphism
preeclampsia
vitamin d receptor
haplotype
Online Access:http://dx.doi.org/10.1080/10641963.2019.1601203

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