Pharmacological aspects of fisetin
Over the past decades, epidemiological studies have concluded that a diet rich in plant-derived products plays a pivotal role in human health. Fisetin (3,3’,4’,7-tetrahydroxyflavone) is a hydrophobic polyphenolic compound primarily found in edible plants (e.g. strawberry, blueberry, apple, grape, pe...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Asian Pacific Journal of Tropical Biomedicine |
| Subjects: | |
| Online Access: | http://www.apjtb.org/article.asp?issn=2221-1691;year=2021;volume=11;issue=1;spage=1;epage=9;aulast=Antika |
| _version_ | 1811275850527539200 |
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| author | Lucia Dwi Antika Rita Marleta Dewi |
| author_facet | Lucia Dwi Antika Rita Marleta Dewi |
| author_sort | Lucia Dwi Antika |
| collection | DOAJ |
| description | Over the past decades, epidemiological studies have concluded that a diet rich in plant-derived products plays a pivotal role in human health. Fisetin (3,3’,4’,7-tetrahydroxyflavone) is a hydrophobic polyphenolic compound primarily found in edible plants (e.g. strawberry, blueberry, apple, grape, persimmon, kiwi, and cucumber). Various preclinical studies have revealed that fisetin exhibits a wide range of pharmacological effects such as antioxidant, anti-inflammatory, anti-carcinogenic, anti-osteoporotic, antimicrobial, and anti-diabetic properties. Therefore, the pharmacological in vitro and in vivo studies on fisetin are discussed in this review. Additionally, this review would be useful for further study regarding the potential of natural products, notably fisetin, and its therapeutic potential for the prevention and treatment of diseases. |
| first_indexed | 2024-04-12T23:46:12Z |
| format | Article |
| id | doaj.art-c2934b9efa25457dbdc7e521650ca136 |
| institution | Directory Open Access Journal |
| issn | 2221-1691 2588-9222 |
| language | English |
| last_indexed | 2024-04-12T23:46:12Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Pacific Journal of Tropical Biomedicine |
| spelling | doaj.art-c2934b9efa25457dbdc7e521650ca1362022-12-22T03:11:51ZengWolters Kluwer Medknow PublicationsAsian Pacific Journal of Tropical Biomedicine2221-16912588-92222021-01-011111910.4103/2221-1691.300726Pharmacological aspects of fisetinLucia Dwi AntikaRita Marleta DewiOver the past decades, epidemiological studies have concluded that a diet rich in plant-derived products plays a pivotal role in human health. Fisetin (3,3’,4’,7-tetrahydroxyflavone) is a hydrophobic polyphenolic compound primarily found in edible plants (e.g. strawberry, blueberry, apple, grape, persimmon, kiwi, and cucumber). Various preclinical studies have revealed that fisetin exhibits a wide range of pharmacological effects such as antioxidant, anti-inflammatory, anti-carcinogenic, anti-osteoporotic, antimicrobial, and anti-diabetic properties. Therefore, the pharmacological in vitro and in vivo studies on fisetin are discussed in this review. Additionally, this review would be useful for further study regarding the potential of natural products, notably fisetin, and its therapeutic potential for the prevention and treatment of diseases.http://www.apjtb.org/article.asp?issn=2221-1691;year=2021;volume=11;issue=1;spage=1;epage=9;aulast=Antikafisetin; anti-inflammatory; anti-diabetic; anti-carcinogenic; anti-osteoporosis; cardioprotective activity |
| spellingShingle | Lucia Dwi Antika Rita Marleta Dewi Pharmacological aspects of fisetin Asian Pacific Journal of Tropical Biomedicine fisetin; anti-inflammatory; anti-diabetic; anti-carcinogenic; anti-osteoporosis; cardioprotective activity |
| title | Pharmacological aspects of fisetin |
| title_full | Pharmacological aspects of fisetin |
| title_fullStr | Pharmacological aspects of fisetin |
| title_full_unstemmed | Pharmacological aspects of fisetin |
| title_short | Pharmacological aspects of fisetin |
| title_sort | pharmacological aspects of fisetin |
| topic | fisetin; anti-inflammatory; anti-diabetic; anti-carcinogenic; anti-osteoporosis; cardioprotective activity |
| url | http://www.apjtb.org/article.asp?issn=2221-1691;year=2021;volume=11;issue=1;spage=1;epage=9;aulast=Antika |
| work_keys_str_mv | AT luciadwiantika pharmacologicalaspectsoffisetin AT ritamarletadewi pharmacologicalaspectsoffisetin |