Microsatellite Instability: Diagnosis, Heterogeneity, Discordance, and Clinical Impact in Colorectal Cancer

Microsatellite Instability: Diagnosis, Heterogeneity, Discordance, and Clinical Impact in Colorectal Cancer

Tumor DNA mismatch repair (MMR) deficiency testing is important to the identification of Lynch syndrome and decision making regarding adjuvant chemotherapy in stage II colorectal cancer (CRC) and has become an indispensable test in metastatic tumors due to the high efficacy of immune checkpoint inhi...

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Bibliographic Details
Main Authors:	Camille Evrard, Gaëlle Tachon, Violaine Randrian, Lucie Karayan-Tapon, David Tougeron
Format:	Article
Language:	English
Published:	MDPI AG 2019-10-01
Series:	Cancers
Subjects:	microsatellite instability colorectal cancer immune checkpoints deficient mismatch repair
Online Access:	https://www.mdpi.com/2072-6694/11/10/1567

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