Exophiala jeanselmei and Rhizopus oryzae Co-infection Post Renal Transplant

Invasive fungal infections are associated with morbidity and mortality in immunocompromised patients. Dematiaceous fungi are being increasingly recognised as human pathogens, particularly in transplant recipients. However, most cases of dematiaceous fungal infections after organ transplantation have...

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Bibliographic Details
Main Authors: Suneeta Meena, Gagandeep Singh, Mragnayani Pandey, Immaculata Xess
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2019-06-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/12948/40304_CE[Ra1]_F(SL)_PF1(AG_OM)_PN(SL).pdf
Description
Summary:Invasive fungal infections are associated with morbidity and mortality in immunocompromised patients. Dematiaceous fungi are being increasingly recognised as human pathogens, particularly in transplant recipients. However, most cases of dematiaceous fungal infections after organ transplantation have been reported as sole aetiological agents. We report a case of fatal, disseminated phaeohyphomycosis with rhinocerebral mucormycosis in post renal transplant patient. Quick diagnosis is challenging and inspite of aggressive management with a combination of surgical and medical therapies, the outcome is poor. Amphotericin B remains the cornerstone in the medical management of mucormycosis and itraconazole in phaeohyphomycosis, still we are short of drugs to fight against such catastrophic organisms.
ISSN:2249-782X
0973-709X