Effect of 10.6-μm CO2 laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial

Abstract Background In this study, we investigated the impact of 10.6-μm CO2 laser moxibustion (LM) on the fastest 15-m walking time in individuals suffering from knee osteoarthritis (KOA). Methods A total of 392 individuals diagnosed with KOA and meeting the specified eligibility criteria were assi...

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Main Authors: Lusheng Chen, Ling Zhao, Ke Cheng, Lin Lin, Fan Wu, Xueyong Shen
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-023-04380-6
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author Lusheng Chen
Ling Zhao
Ke Cheng
Lin Lin
Fan Wu
Xueyong Shen
author_facet Lusheng Chen
Ling Zhao
Ke Cheng
Lin Lin
Fan Wu
Xueyong Shen
author_sort Lusheng Chen
collection DOAJ
description Abstract Background In this study, we investigated the impact of 10.6-μm CO2 laser moxibustion (LM) on the fastest 15-m walking time in individuals suffering from knee osteoarthritis (KOA). Methods A total of 392 individuals diagnosed with KOA and meeting the specified eligibility criteria were assigned randomly into two groups: the LM treatment group and the sham LM control group (ratio 1:1). Both groups received either LM therapy or simulated LM therapy to address the affected area of the knee joint. This treatment was administered three times a week for a duration of 4 weeks. Results In the LM group, the fastest 15-m walking times at both Week 4 and Week 12 were significantly reduced compared to the times before treatment (all P < 0.05). However, in the sham LM group, there were no notable differences in the fastest 15-m walking times after treatment (all P > 0.05). Moreover, the LM group exhibited shorter 15-m walking times than the sham LM group at both Week 4 and Week 12 (all P < 0.05). Conclusion The use of CO2 LM can lead to a substantial enhancement in the fastest 15-m walking time of individuals suffering from KOA, and its therapeutic impact can last for a minimum of 8 weeks post-treatment. The fastest 15-m walking time serves as an indicator of alterations in the walking capacity of patients with KOA.
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spelling doaj.art-c29974b4d37c44aa947ef9eb1b0a3dc72023-11-26T13:48:46ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2023-11-011811710.1186/s13018-023-04380-6Effect of 10.6-μm CO2 laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trialLusheng Chen0Ling Zhao1Ke Cheng2Lin Lin3Fan Wu4Xueyong Shen5Shanghai Key Laboratory of Acupuncture Mechanism and Acupoint Function, Fudan UniversitySchool of Acupuncture-Moxibustion and Tuina, Shanghai University of Traditional Chinese MedicineSchool of Acupuncture-Moxibustion and Tuina, Shanghai University of Traditional Chinese MedicineSchool of Acupuncture-Moxibustion and Tuina, Shanghai University of Traditional Chinese MedicineSchool of Acupuncture-Moxibustion and Tuina, Shanghai University of Traditional Chinese MedicineSchool of Acupuncture-Moxibustion and Tuina, Shanghai University of Traditional Chinese MedicineAbstract Background In this study, we investigated the impact of 10.6-μm CO2 laser moxibustion (LM) on the fastest 15-m walking time in individuals suffering from knee osteoarthritis (KOA). Methods A total of 392 individuals diagnosed with KOA and meeting the specified eligibility criteria were assigned randomly into two groups: the LM treatment group and the sham LM control group (ratio 1:1). Both groups received either LM therapy or simulated LM therapy to address the affected area of the knee joint. This treatment was administered three times a week for a duration of 4 weeks. Results In the LM group, the fastest 15-m walking times at both Week 4 and Week 12 were significantly reduced compared to the times before treatment (all P < 0.05). However, in the sham LM group, there were no notable differences in the fastest 15-m walking times after treatment (all P > 0.05). Moreover, the LM group exhibited shorter 15-m walking times than the sham LM group at both Week 4 and Week 12 (all P < 0.05). Conclusion The use of CO2 LM can lead to a substantial enhancement in the fastest 15-m walking time of individuals suffering from KOA, and its therapeutic impact can last for a minimum of 8 weeks post-treatment. The fastest 15-m walking time serves as an indicator of alterations in the walking capacity of patients with KOA.https://doi.org/10.1186/s13018-023-04380-6Acupuncture therapyCO2 laser moxibustionKnee jointOsteoarthritisWalking time
spellingShingle Lusheng Chen
Ling Zhao
Ke Cheng
Lin Lin
Fan Wu
Xueyong Shen
Effect of 10.6-μm CO2 laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial
Journal of Orthopaedic Surgery and Research
Acupuncture therapy
CO2 laser moxibustion
Knee joint
Osteoarthritis
Walking time
title Effect of 10.6-μm CO2 laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial
title_full Effect of 10.6-μm CO2 laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial
title_fullStr Effect of 10.6-μm CO2 laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial
title_full_unstemmed Effect of 10.6-μm CO2 laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial
title_short Effect of 10.6-μm CO2 laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial
title_sort effect of 10 6 μm co2 laser moxibustion on the fastest 15 m walking time in patients with knee osteoarthritis a double blind sham controlled multi site randomized trial
topic Acupuncture therapy
CO2 laser moxibustion
Knee joint
Osteoarthritis
Walking time
url https://doi.org/10.1186/s13018-023-04380-6
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