Effects of Atorvastatin on T‐Cell Activation and Apoptosis in Systemic Lupus Erythematosus and Novel Simulated Interactions With C‐Reactive Protein and Interleukin 6
Objective We study activation of T helper 17 (Th17) and regulatory T (Treg) cells and induction of apoptosis in cells from patients with systemic lupus erythematosus (SLE) compared with controls and effects of atorvastatin and its simulated interactions with other compounds. Methods Mononuclear cell...
Main Authors: | Jitong Sun, Pritam Kumar Panda, Shailesh Kumar Samal, Rajeev Ahuja, Sofia Ajeganova, Ingiäld Hafström, Anquan Liu, Johan Frostegård |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2021-09-01
|
Series: | ACR Open Rheumatology |
Online Access: | https://doi.org/10.1002/acr2.11305 |
Similar Items
-
Similar progression of carotid intima–media thickness in 7-year surveillance of patients with mild SLE and controls, but this progression is still promoted by dyslipidaemia, lower HDL levels, hypertension, history of lupus nephritis and a higher prednisolone usage in patients
by: Thomas Gustafsson, et al.
Published: (2020-12-01) -
Higher levels of anti-phosphorylcholine autoantibodies in early rheumatoid arthritis indicate lower risk of incident cardiovascular events
by: Sofia Ajeganova, et al.
Published: (2021-07-01) -
Low levels of PCSK9 are associated with remission in patients with rheumatoid arthritis treated with anti-TNF-α: potential underlying mechanisms
by: Johan Frostegård, et al.
Published: (2021-01-01) -
Antibodies Against Phosphorylcholine Among 60-Year-Olds: Clinical Role and Simulated Interactions
by: Shailesh Kumar Samal, et al.
Published: (2022-04-01) -
Anti-citrullinated protein antibodies are associated with osteopenia but not with pain at diagnosis of rheumatoid arthritis: data from the BARFOT cohort
by: Ingiäld Hafström, et al.
Published: (2019-02-01)