Impact of Electrical Pulse Pattern on Red Blood Cell Membranous Electroporation
The impact of the pattern of a pulse electrical field generated by a defibrillator discharge on the efficiency of membranous electroporation was studied in a model experiment on human erythrocytic suspension. The initial temperature and time parameters of the model were substantiated. The rate of ce...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2005-02-01
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| Series: | Общая реаниматология |
| Online Access: | https://www.reanimatology.com/rmt/article/view/1321 |
| _version_ | 1797874429447897088 |
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| author | Ye. K. Kozlova V. V. Moroz M. S. Bogushevich P. Yu. Alekseyeva A. M. Chernysh |
| author_facet | Ye. K. Kozlova V. V. Moroz M. S. Bogushevich P. Yu. Alekseyeva A. M. Chernysh |
| author_sort | Ye. K. Kozlova |
| collection | DOAJ |
| description | The impact of the pattern of a pulse electrical field generated by a defibrillator discharge on the efficiency of membranous electroporation was studied in a model experiment on human erythrocytic suspension. The initial temperature and time parameters of the model were substantiated. The rate of cellular hemolysis under the action of two impulses was shown to be increased by 1.2—3.5 times as compared with that under the action of one impulse. Electroporation was more effective and its threshold was lower under the action of two heterodirectional pulses as compared with that under the action of two unidirectional ones. These dependencies are statistical. |
| first_indexed | 2024-04-10T01:31:57Z |
| format | Article |
| id | doaj.art-c29c6ace936a44f1993375ee10a76a2c |
| institution | Directory Open Access Journal |
| issn | 1813-9779 2411-7110 |
| language | English |
| last_indexed | 2024-04-10T01:31:57Z |
| publishDate | 2005-02-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj.art-c29c6ace936a44f1993375ee10a76a2c2023-03-13T09:32:45ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102005-02-0111424610.15360/1813-9779-2005-1-42-461321Impact of Electrical Pulse Pattern on Red Blood Cell Membranous ElectroporationYe. K. Kozlova0V. V. Moroz1M. S. Bogushevich2P. Yu. Alekseyeva3A. M. Chernysh4ГУ НИИ общей реаниматологии РАМН, Москва, Московская медицинская академия им. И.М. СеченоваГУ НИИ общей реаниматологии РАМН, Москва, Московская медицинская академия им. И.М. СеченоваГУ НИИ общей реаниматологии РАМН, Москва, Московская медицинская академия им. И.М. СеченоваГУ НИИ общей реаниматологии РАМН, Москва, Московская медицинская академия им. И.М. СеченоваГУ НИИ общей реаниматологии РАМН, Москва, Московская медицинская академия им. И.М. СеченоваThe impact of the pattern of a pulse electrical field generated by a defibrillator discharge on the efficiency of membranous electroporation was studied in a model experiment on human erythrocytic suspension. The initial temperature and time parameters of the model were substantiated. The rate of cellular hemolysis under the action of two impulses was shown to be increased by 1.2—3.5 times as compared with that under the action of one impulse. Electroporation was more effective and its threshold was lower under the action of two heterodirectional pulses as compared with that under the action of two unidirectional ones. These dependencies are statistical.https://www.reanimatology.com/rmt/article/view/1321 |
| spellingShingle | Ye. K. Kozlova V. V. Moroz M. S. Bogushevich P. Yu. Alekseyeva A. M. Chernysh Impact of Electrical Pulse Pattern on Red Blood Cell Membranous Electroporation Общая реаниматология |
| title | Impact of Electrical Pulse Pattern on Red Blood Cell Membranous Electroporation |
| title_full | Impact of Electrical Pulse Pattern on Red Blood Cell Membranous Electroporation |
| title_fullStr | Impact of Electrical Pulse Pattern on Red Blood Cell Membranous Electroporation |
| title_full_unstemmed | Impact of Electrical Pulse Pattern on Red Blood Cell Membranous Electroporation |
| title_short | Impact of Electrical Pulse Pattern on Red Blood Cell Membranous Electroporation |
| title_sort | impact of electrical pulse pattern on red blood cell membranous electroporation |
| url | https://www.reanimatology.com/rmt/article/view/1321 |
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