Delayed Treatment with α-Phenyl-N-tert-butyl Nitrone (PBN) Attenuates Secondary Mitochondrial Dysfunction after Transient Focal Cerebral Ischemia in the Rat

Delayed Treatment with α-Phenyl-N-tert-butyl Nitrone (PBN) Attenuates Secondary Mitochondrial Dysfunction after Transient Focal Cerebral Ischemia in the Rat

The present experiments were undertaken to explore the mechanisms of secondary brain damage in focal ischemia of long duration (2 h), followed by recirculation. Recirculation has previously been found to cause partial recovery and secondary deterioration of cellular bioenergetic state, the subsequen...

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Bibliographic Details
Main Authors:	Satoshi Kuroda, Ken-ichiro Katsura, Lars Hillered, Timothy E. Bates, Bo K. Siesjö
Format:	Article
Language:	English
Published:	Elsevier 1996-04-01
Series:	Neurobiology of Disease
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996196900157

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