Glucose fluctuation promotes mitochondrial dysfunctions in the cardiomyocyte cell line HL-1.
<h4>Aims</h4>Glycemic variability has been suggested as a risk factor for diabetes complications but the precise deleterious mechanisms remain poorly understood. Since mitochondria are the main source of energy in heart and cardiovascular diseases remain the first cause of death in patie...
Main Authors: | Patrick Mordel, Fanny Fontaine, Quentin Dupas, Michael Joubert, Stéphane Allouche |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0289475 |
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