Spatial distribution of Mycobacterium tuberculosis mRNA and secreted antigens in acid-fast negative human antemortem and resected tissueResearch in context

Spatial distribution of Mycobacterium tuberculosis mRNA and secreted antigens in acid-fast negative human antemortem and resected tissueResearch in context

Summary: Background: The ability to detect evidence of Mycobacterium tuberculosis (Mtb) infection within human tissues is critical to the study of Mtb physiology, tropism, and spatial distribution within TB lesions. The capacity of the widely-used Ziehl-Neelsen (ZN) staining method for identifying...

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Bibliographic Details
Main Authors: Kievershen Nargan, Joel N. Glasgow, Sajid Nadeem, Threnesan Naidoo, Gordon Wells, Robert L. Hunter, Anneka Hutton, Kapongo Lumamba, Mpumelelo Msimang, Paul V. Benson, Adrie J.C. Steyn
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:EBioMedicine
Subjects:
Tuberculosis
Antigen
Ziehl-Neelsen
RNAscope
Diagnosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424002317

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