Eternal dilemma of the interplay between coexisting tuberculosis and malignancy: Clinical scenario of coexisting submandibular carcinoma with disseminated tuberculosis: A case report

Tuberculosis (TB) and malignancy are two lethal diseases that cause significant morbidity and mortality in developing countries like India. Extrapulmonary tuberculosis (TB) constitutes about 15 to 20 per cent of all cases of tuberculosis with lymph nodes being the most common site of involvement.1 M...

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Main Author: Manjari Shah
Format: Article
Language:English
Published: Manipal College of Medical Sciences, Pokhara 2016-01-01
Series:Asian Journal of Medical Sciences
Subjects:
Online Access:https://www.nepjol.info/index.php/AJMS/article/view/13634
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author Manjari Shah
author_facet Manjari Shah
author_sort Manjari Shah
collection DOAJ
description Tuberculosis (TB) and malignancy are two lethal diseases that cause significant morbidity and mortality in developing countries like India. Extrapulmonary tuberculosis (TB) constitutes about 15 to 20 per cent of all cases of tuberculosis with lymph nodes being the most common site of involvement.1 Malignant transformation in pleomorphic adenoma lead to carcinoma ex pleomorphic adenoma (CXPA). CXPA of the salivary glands, however, is relatively uncommon, accounting for 3.6 % of all salivary gland neoplasms and 11.7 % of all malignant salivary gland neoplasms.2 Here we report a case of carcinoma ex pleomorphic adenoma of submandibular gland which presented as a swelling in submandibular region along with generalized lymphadenopathy which mimicked widespread metastases but later on histologically showed tuberculosis.
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spelling doaj.art-c2abf5da3c0c4c33bcc18b93b42c0cb62022-12-22T01:06:52ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762016-01-0173115117https://doi.org/10.3126/ajms.v7i3.13634Eternal dilemma of the interplay between coexisting tuberculosis and malignancy: Clinical scenario of coexisting submandibular carcinoma with disseminated tuberculosis: A case reportManjari Shah 0DNB Resident, Department of Radiation Oncology, Max Superspeciality hospital, Vaishali, Ghaziabad http://orcid.org/0000-0001-9665-9624Tuberculosis (TB) and malignancy are two lethal diseases that cause significant morbidity and mortality in developing countries like India. Extrapulmonary tuberculosis (TB) constitutes about 15 to 20 per cent of all cases of tuberculosis with lymph nodes being the most common site of involvement.1 Malignant transformation in pleomorphic adenoma lead to carcinoma ex pleomorphic adenoma (CXPA). CXPA of the salivary glands, however, is relatively uncommon, accounting for 3.6 % of all salivary gland neoplasms and 11.7 % of all malignant salivary gland neoplasms.2 Here we report a case of carcinoma ex pleomorphic adenoma of submandibular gland which presented as a swelling in submandibular region along with generalized lymphadenopathy which mimicked widespread metastases but later on histologically showed tuberculosis.https://www.nepjol.info/index.php/AJMS/article/view/13634tuberculosismalignancysalivary glandlymphadenopathy
spellingShingle Manjari Shah
Eternal dilemma of the interplay between coexisting tuberculosis and malignancy: Clinical scenario of coexisting submandibular carcinoma with disseminated tuberculosis: A case report
Asian Journal of Medical Sciences
tuberculosis
malignancy
salivary gland
lymphadenopathy
title Eternal dilemma of the interplay between coexisting tuberculosis and malignancy: Clinical scenario of coexisting submandibular carcinoma with disseminated tuberculosis: A case report
title_full Eternal dilemma of the interplay between coexisting tuberculosis and malignancy: Clinical scenario of coexisting submandibular carcinoma with disseminated tuberculosis: A case report
title_fullStr Eternal dilemma of the interplay between coexisting tuberculosis and malignancy: Clinical scenario of coexisting submandibular carcinoma with disseminated tuberculosis: A case report
title_full_unstemmed Eternal dilemma of the interplay between coexisting tuberculosis and malignancy: Clinical scenario of coexisting submandibular carcinoma with disseminated tuberculosis: A case report
title_short Eternal dilemma of the interplay between coexisting tuberculosis and malignancy: Clinical scenario of coexisting submandibular carcinoma with disseminated tuberculosis: A case report
title_sort eternal dilemma of the interplay between coexisting tuberculosis and malignancy clinical scenario of coexisting submandibular carcinoma with disseminated tuberculosis a case report
topic tuberculosis
malignancy
salivary gland
lymphadenopathy
url https://www.nepjol.info/index.php/AJMS/article/view/13634
work_keys_str_mv AT manjarishah eternaldilemmaoftheinterplaybetweencoexistingtuberculosisandmalignancyclinicalscenarioofcoexistingsubmandibularcarcinomawithdisseminatedtuberculosisacasereport