Aspirin Augments IgE-Mediated Histamine Release from Human Peripheral Basophils via Syk Kinase Activation

Aspirin Augments IgE-Mediated Histamine Release from Human Peripheral Basophils via Syk Kinase Activation

Background: Non-steroidal anti-inflammatory drugs (NSAIDs), especially aspirin, and food additives (FAs) may exacerbate allergic symptoms in patients with chronic idiopathic urticaria and food-dependent exercise- induced anaphylaxis (FDEIA). Augmentation of histamine release from human mast cells an...

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Bibliographic Details
Main Authors: Hiroaki Matsuo, Tomoharu Yokooji, Hironobu Morita, Mina Ooi, Kana Urata, Kaori Ishii, Shunsuke Takahagi, Yuhki Yanase, Takaaki Hiragun, Shoji Mihara, Michihiro Hide
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Allergology International
Subjects:
aspirin
basophils
food additives
histamine release
NSAID
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015301696

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