Food intake regulation during pregnancy and lactation in mice with reduced activity of the melanocortin system

Food intake regulation during pregnancy and lactation in mice with reduced activity of the melanocortin system

Hypothalamic melanortin receptor (MCR) activation inhibits appetite. Neuropeptide Y (NPY) and Agouti Related Protein (AgRP) are coexpressed in some hypothalamic neurons and stimulate feeding, NPY via inhibition of MCR-expressing neurons, and AgRP via MCR4 antagonism. Mutation yellow at the mouse ago...

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Bibliographic Details
Main Authors: E. N. Makarova, I. V. Romanova, N. M. Bazhan
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2016-05-01
Series:Вавиловский журнал генетики и селекции
Subjects:
ау mice
food intake
pregnancy
lactation
melanocortin receptors
npy
agrp
Online Access:https://vavilov.elpub.ru/jour/article/view/578

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