Gold nanocarriers for transport of oligonucleotides across brain endothelial cells
Treatment of diseases that affect the CNS by gene therapy requires delivery of oligonucleotides to target cells within the brain. As the blood brain barrier prevents movement of large biomolecules, current approaches involve direct injection of the oligonucleotides, which is invasive and may have on...
Main Authors: | Nayab Fatima, Radka Gromnicova, Jane Loughlin, Basil Sharrack, David Male, Yi Cao |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498062/?tool=EBI |
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