miR-5000-3p confers oxaliplatin resistance by targeting ubiquitin-specific peptidase 49 in colorectal cancer
Abstract Colorectal cancer (CRC) is the most common form of gastrointestinal malignancies. A growing number of reports focusing on oxaliplatin (OXA) resistance in CRC treatment have revealed that drug resistance is an urgent issue in clinical applications, especially for finding effective therapeuti...
Main Authors: | Yan-yan Zhuang, Wa Zhong, Zhong-sheng Xia, Shu-zhen Lin, Man chung Chan, Ke Jiang, Wen-fei Li, Xin-yi Xu |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-06-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-021-00494-0 |
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