Impaired pulmonary function after treatment for tuberculosis: the end of the disease?

ABSTRACT Objective: To evaluate the prevalence of pulmonary function abnormalities and to investigate the factors affecting lung function in patients treated for pulmonary tuberculosis. Methods: A total of 214 consecutive patients (132 men and 82 women; 20-82 years of age), treated for pulmonary...

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Main Authors: Mikhail Ivanovich Chushkin, Oleg Nikolayevich Ots
Format: Article
Language:English
Published: Sociedade Brasileira de Pneumologia e Tisiologia
Series:Jornal Brasileiro de Pneumologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132017000100038&lng=en&tlng=en
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author Mikhail Ivanovich Chushkin
Oleg Nikolayevich Ots
author_facet Mikhail Ivanovich Chushkin
Oleg Nikolayevich Ots
author_sort Mikhail Ivanovich Chushkin
collection DOAJ
description ABSTRACT Objective: To evaluate the prevalence of pulmonary function abnormalities and to investigate the factors affecting lung function in patients treated for pulmonary tuberculosis. Methods: A total of 214 consecutive patients (132 men and 82 women; 20-82 years of age), treated for pulmonary tuberculosis and followed at a local dispensary, underwent spirometry and plethysmography at least one year after treatment. Results: Pulmonary impairment was present in 102 (47.7%) of the 214 patients evaluated. The most common functional alteration was obstructive lung disease (seen in 34.6%). Of the 214 patients, 60 (28.0%) showed reduced pulmonary function (FEV1 below the lower limit of normal). Risk factors for reduced pulmonary function were having had culture-positive pulmonary tuberculosis in the past, being over 50 years of age, having recurrent tuberculosis, and having a lower level of education. Conclusions: Nearly half of all tuberculosis patients evolve to impaired pulmonary function. That underscores the need for pulmonary function testing after the end of treatment.
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spelling doaj.art-c2bb3427d80f4b10a732bfe925b8f0222022-12-22T03:43:26ZengSociedade Brasileira de Pneumologia e TisiologiaJornal Brasileiro de Pneumologia1806-3756431384310.1590/s1806-37562016000000053S1806-37132017000100038Impaired pulmonary function after treatment for tuberculosis: the end of the disease?Mikhail Ivanovich ChushkinOleg Nikolayevich OtsABSTRACT Objective: To evaluate the prevalence of pulmonary function abnormalities and to investigate the factors affecting lung function in patients treated for pulmonary tuberculosis. Methods: A total of 214 consecutive patients (132 men and 82 women; 20-82 years of age), treated for pulmonary tuberculosis and followed at a local dispensary, underwent spirometry and plethysmography at least one year after treatment. Results: Pulmonary impairment was present in 102 (47.7%) of the 214 patients evaluated. The most common functional alteration was obstructive lung disease (seen in 34.6%). Of the 214 patients, 60 (28.0%) showed reduced pulmonary function (FEV1 below the lower limit of normal). Risk factors for reduced pulmonary function were having had culture-positive pulmonary tuberculosis in the past, being over 50 years of age, having recurrent tuberculosis, and having a lower level of education. Conclusions: Nearly half of all tuberculosis patients evolve to impaired pulmonary function. That underscores the need for pulmonary function testing after the end of treatment.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132017000100038&lng=en&tlng=enRespiratory function testsTuberculosis, pulmonarySpirometryLung diseases, obstructive
spellingShingle Mikhail Ivanovich Chushkin
Oleg Nikolayevich Ots
Impaired pulmonary function after treatment for tuberculosis: the end of the disease?
Jornal Brasileiro de Pneumologia
Respiratory function tests
Tuberculosis, pulmonary
Spirometry
Lung diseases, obstructive
title Impaired pulmonary function after treatment for tuberculosis: the end of the disease?
title_full Impaired pulmonary function after treatment for tuberculosis: the end of the disease?
title_fullStr Impaired pulmonary function after treatment for tuberculosis: the end of the disease?
title_full_unstemmed Impaired pulmonary function after treatment for tuberculosis: the end of the disease?
title_short Impaired pulmonary function after treatment for tuberculosis: the end of the disease?
title_sort impaired pulmonary function after treatment for tuberculosis the end of the disease
topic Respiratory function tests
Tuberculosis, pulmonary
Spirometry
Lung diseases, obstructive
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132017000100038&lng=en&tlng=en
work_keys_str_mv AT mikhailivanovichchushkin impairedpulmonaryfunctionaftertreatmentfortuberculosistheendofthedisease
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