Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery

Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery

Summary: Autophagy is a catabolic process involving capture of cytoplasmic materials into double-membraned autophagosomes that subsequently fuse with lysosomes for degradation of the materials by lysosomal hydrolases. One of the least understood components of the autophagy machinery is the transmemb...

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Bibliographic Details
Main Authors: Carlos M. Guardia, Xiao-Feng Tan, Tengfei Lian, Mitra S. Rana, Wenchang Zhou, Eric T. Christenson, Augustus J. Lowry, José D. Faraldo-Gómez, Juan S. Bonifacino, Jiansen Jiang, Anirban Banerjee
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Cell Reports
Subjects:
ATG9A
autophagosome
autophagy
cryo-EM
molecular dynamics
transmembrane protein
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720308184

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