Improved lifestyle is associated with improved depression, anxiety and well-being over time in UK healthcare professionals during the COVID-19 pandemic: insights from the CoPE-HCP cohort study

Background One potential modifiable factor to improve the mental health of healthcare professionals (HCPs) during the pandemic is lifestyle.Aims This study aimed to assess whether an improved lifestyle during the pandemic is associated with improved mental health symptoms and mental well-being in HC...

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Main Authors: Ajay Gupta, Vikas Kapil, Mohammed Y Khanji, Sher May Ng, George Collett, Thomas Godec, Carmela Maniero, Imrana Siddiqui, Jaya Gupta
Format: Article
Language:English
Published: BMJ Publishing Group 2023-01-01
Series:General Psychiatry
Online Access:https://gpsych.bmj.com/content/36/1/e100908.full
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author Ajay Gupta
Vikas Kapil
Mohammed Y Khanji
Sher May Ng
George Collett
Thomas Godec
Carmela Maniero
Imrana Siddiqui
Jaya Gupta
author_facet Ajay Gupta
Vikas Kapil
Mohammed Y Khanji
Sher May Ng
George Collett
Thomas Godec
Carmela Maniero
Imrana Siddiqui
Jaya Gupta
author_sort Ajay Gupta
collection DOAJ
description Background One potential modifiable factor to improve the mental health of healthcare professionals (HCPs) during the pandemic is lifestyle.Aims This study aimed to assess whether an improved lifestyle during the pandemic is associated with improved mental health symptoms and mental well-being in HCPs over time.Methods This was a cohort study involving an online survey distributed at two separate time points during the pandemic (baseline (July–September 2020) and follow-up (December 2020–March 2021)) to HCPs working in primary or secondary care in the UK. Both surveys assessed for major depressive disorder (MDD) (Patient Health Questionnaire-9 (PHQ-9)), generalised anxiety disorder (GAD) (Generalised Anxiety Disorder-7 (GAD-7)), mental well-being (Short Warwick-Edinburgh Mental Well-being Score (SWEMWBS)) and self-reported lifestyle change (compared with the start of the pandemic) on multiple domains. Cumulative scores were calculated to estimate overall lifestyle change compared with that before the pandemic (at both baseline and follow-up). At each time point, separate logistic regression models were constructed to relate the lifestyle change score with the presence of MDD, GAD and low mental well-being. Linear regression models were also developed relating the change in lifestyle scores from baseline to follow-up to changes in PHQ-9, GAD-7 and SWEMWBS scores.Results 613 HCPs completed both baseline assessment and follow-up assessment. Consistent significant cross-sectional associations between increased lifestyle change scores and a reduced risk of MDD, GAD and low mental well-being were observed at both baseline and follow-up. Over the study period, a whole unit increase in the change in novel scores (ie, improved overall lifestyle) over 4 months was inversely associated with changes in PHQ-9 (adjusted coefficient: −0.51, 95% confidence interval (CI): −0.73 to −0.30, p<0.001) and GAD-7 scores (adjusted coefficient: −0.32, 95% CI: −0.53 to −0.10, p=0.004) and positively associated with the change in SWEMWBS scores (adjusted coefficient: 0.37, 95% CI: 0.18 to 0.55, p<0.001).Conclusions Improved lifestyle over time is associated with improved mental health and mental well-being in HCPs during the pandemic. Improving lifestyle could be a recommended intervention for HCPs to help mitigate the mental health impact during the current and future pandemics.Trial registration number NCT04433260.
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spelling doaj.art-c2bcb7c8d6474ba5b67b9f24e714d0a32023-07-29T02:55:06ZengBMJ Publishing GroupGeneral Psychiatry2517-729X2023-01-0136110.1136/gpsych-2022-100908Improved lifestyle is associated with improved depression, anxiety and well-being over time in UK healthcare professionals during the COVID-19 pandemic: insights from the CoPE-HCP cohort studyAjay Gupta0Vikas Kapil1Mohammed Y Khanji2Sher May Ng3George Collett4Thomas Godec5Carmela Maniero6Imrana Siddiqui7Jaya Gupta8William Harvey Research Institute, Queen Mary University of London, London, UKWilliam Harvey Research Institute, Queen Mary University of London, London, UKWilliam Harvey Research Institute, Queen Mary University of London, London, UKDepartment of Cardiology, Barts Heart Centre, Saint Bartholomew`s Hospital, Barts Health NHS Trust, London, UKWilliam Harvey Research Institute, Queen Mary University of London, London, UKWilliam Harvey Research Institute, Queen Mary University of London, London, UKWilliam Harvey Research Institute, Queen Mary University of London, London, UKWellbeing Hub, Newham Training Hub, London, UKChild and Adolescent Mental Health Service, South West London and St George`s Mental Health NHS Trust, London, UKBackground One potential modifiable factor to improve the mental health of healthcare professionals (HCPs) during the pandemic is lifestyle.Aims This study aimed to assess whether an improved lifestyle during the pandemic is associated with improved mental health symptoms and mental well-being in HCPs over time.Methods This was a cohort study involving an online survey distributed at two separate time points during the pandemic (baseline (July–September 2020) and follow-up (December 2020–March 2021)) to HCPs working in primary or secondary care in the UK. Both surveys assessed for major depressive disorder (MDD) (Patient Health Questionnaire-9 (PHQ-9)), generalised anxiety disorder (GAD) (Generalised Anxiety Disorder-7 (GAD-7)), mental well-being (Short Warwick-Edinburgh Mental Well-being Score (SWEMWBS)) and self-reported lifestyle change (compared with the start of the pandemic) on multiple domains. Cumulative scores were calculated to estimate overall lifestyle change compared with that before the pandemic (at both baseline and follow-up). At each time point, separate logistic regression models were constructed to relate the lifestyle change score with the presence of MDD, GAD and low mental well-being. Linear regression models were also developed relating the change in lifestyle scores from baseline to follow-up to changes in PHQ-9, GAD-7 and SWEMWBS scores.Results 613 HCPs completed both baseline assessment and follow-up assessment. Consistent significant cross-sectional associations between increased lifestyle change scores and a reduced risk of MDD, GAD and low mental well-being were observed at both baseline and follow-up. Over the study period, a whole unit increase in the change in novel scores (ie, improved overall lifestyle) over 4 months was inversely associated with changes in PHQ-9 (adjusted coefficient: −0.51, 95% confidence interval (CI): −0.73 to −0.30, p<0.001) and GAD-7 scores (adjusted coefficient: −0.32, 95% CI: −0.53 to −0.10, p=0.004) and positively associated with the change in SWEMWBS scores (adjusted coefficient: 0.37, 95% CI: 0.18 to 0.55, p<0.001).Conclusions Improved lifestyle over time is associated with improved mental health and mental well-being in HCPs during the pandemic. Improving lifestyle could be a recommended intervention for HCPs to help mitigate the mental health impact during the current and future pandemics.Trial registration number NCT04433260.https://gpsych.bmj.com/content/36/1/e100908.full
spellingShingle Ajay Gupta
Vikas Kapil
Mohammed Y Khanji
Sher May Ng
George Collett
Thomas Godec
Carmela Maniero
Imrana Siddiqui
Jaya Gupta
Improved lifestyle is associated with improved depression, anxiety and well-being over time in UK healthcare professionals during the COVID-19 pandemic: insights from the CoPE-HCP cohort study
General Psychiatry
title Improved lifestyle is associated with improved depression, anxiety and well-being over time in UK healthcare professionals during the COVID-19 pandemic: insights from the CoPE-HCP cohort study
title_full Improved lifestyle is associated with improved depression, anxiety and well-being over time in UK healthcare professionals during the COVID-19 pandemic: insights from the CoPE-HCP cohort study
title_fullStr Improved lifestyle is associated with improved depression, anxiety and well-being over time in UK healthcare professionals during the COVID-19 pandemic: insights from the CoPE-HCP cohort study
title_full_unstemmed Improved lifestyle is associated with improved depression, anxiety and well-being over time in UK healthcare professionals during the COVID-19 pandemic: insights from the CoPE-HCP cohort study
title_short Improved lifestyle is associated with improved depression, anxiety and well-being over time in UK healthcare professionals during the COVID-19 pandemic: insights from the CoPE-HCP cohort study
title_sort improved lifestyle is associated with improved depression anxiety and well being over time in uk healthcare professionals during the covid 19 pandemic insights from the cope hcp cohort study
url https://gpsych.bmj.com/content/36/1/e100908.full
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