Therapeutic Targeting of Pancreatic Cancer via EphA2 Dimeric Agonistic Agents

Recently, we reported on potent EphA2 targeting compounds and demonstrated that dimeric versions of such agents can exhibit remarkably increased agonistic activity in cellular assays compared to the monomers. Here we further characterize the activity of dimeric compounds at the structural, biochemic...

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Bibliographic Details
Main Authors: Ahmed F. Salem, Luca Gambini, Parima Udompholkul, Carlo Baggio, Maurizio Pellecchia
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/13/5/90